The human pulmonary surfactant protein A (hSP-A) has been implicated in the early capture and phagocytosis of the pathogenic Mycobacterium tuberculosis by alveolar macrophages. In this report, we examined the interaction of alveolar proteinosis patient hSP-A with Mycobacterium bovis BCG, the vaccinating strain, as a model of pathogenic mycobacteria, and Mycobacterium smegmatis, a nonpathogenic ...

Henoch-Schonlein purpura (HSP) is an IgA-mediated disorder that most commonly occurs in children. Its etiology and pathogenesis remain unknown. In recent years, numerous studies have pointed to a dysfunction of T cells in the pathogenesis of HSP. Here, we will review the epidemiology, clinical and molecular characteristics of HSP, as well as abnormalities of Th cell subsets in this disorder. Fi...

To summarize the experience of diagnosing and treating patients with Henoch-Schönlein purpura (HSP)-related pancreatitis, a systematic review of previously published cases was conducted. Among 13 reported cases, there were six males and seven females whose age from 3 to 70 years. The clinical features of these patients indicated that acute pancreatitis could be the initial manifestation of HSP,...

Proteins, under conditions of cellular stress, typically tend to unfold and form lethal aggregates leading neurological diseases like Parkinson's Alzheimer's. A clear understanding the that favor dis-aggregation restore cell its healthy state after they have been stressed is therefore important in dealing with these diseases. The heat shock response (HSR) mechanism a signaling network deals und...

The influence of two different stocking densities (0.20 m2/animal and 0.40 m2/animal) in transit under the hot, humid tropical conditions on heat shock protein (hsp) 70 induction was investigated in 60 Boer does. The animals were road transported for 3 h and the control group was kept under normal conditions in the farm. Irrespective of stocking density, transportation significantly increased h...

Henoch–Schönlein purpura (HSP) is a systemic small vessel vasculitis, characterized by the deposition of immune complexes, mainly polymeric IgA1 and C3, in the skin, gastrointestinal tract, joints, and kidneys w1x. Although the aetiology remains unknown, HSP is often associated with infectious agents. All ages may be affected although it is more common in children, and has a male predominance. ...

Immunofluorescent staining was used to detect in situ alterations in inducible heat shock (stress) protein (HSP)-70 production and DNA fragmentation (indicative of apoptotic cell death) in luteal tissues obtained from sheep after in vivo administration of a luteolytic dose of PGF2 alpha. Accumulation of HSP-70 was localized to PG-sensitive (i.e., large) luteal cells. Cytoplasmic HSP-70 increase...

Henoch-Schonlein purpura (HSP) is the most common form of acute vasculitis primarily affecting children. Clinical features include skin rashes, arthritis, abdominal pain and nephritis. Skin biopsy on immunofluorescence often reveals granular depositions of immunoglobulin A (IgA) and C3 within the walls of the dermal vessels as well as in the connective tissue of the upper dermis. The diversity ...

[Purpose] This review article is designed to expose the application of sonography in shoulder pain after stroke. [Methods] A range of databases was searched to identify articles that address sonography examination, with or without ultrasound guided corticosteroid injection for hemiplegic shoulder pain (HSP). The electronic databases of PubMed, CENTRAL, CINAHL, Cochrane Library, Medline were sea...

Introduction: Hereditary spastic paraplegia (HSP) is the term for a group of neurological disorders characterized by progressive spasticity and muscle weakness in lower limbs. Its etiology genetic has been associated with mutations more than 60 genes. HSP rare may be useful differential diagnosis cerebral palsy. Case presentation: 16-year-old male due to mutation NIPA1 gene:c.316G>A (p. Gly1...