Background: Previously published data on any association of the fat mass and obesity-associated (FTO) gene with breast cancer risk remain inconclusive. Therefore, we conducted the present meta-analysis of links between breast cancer and the FTO rs9939609 polymorphism. Methods: We have conducted a systematic review of the English literature by searching PubMed, Google Scholar and ISI Web of Know...

The fat mass and obesity-associated (FTO) gene is currently recognized as the most robust predictor of polygenic obesity. We investigated associations between the FTO rs1421085 and rs17817449 polymorphisms and the FTO rs1421085-rs17817449 haplotype and dietary intake, eating behavior, physical activity, and psychological health, as well as the effect of these associations on BMI. N = 133 treatm...

Although FTO is an established obesity-susceptibility locus, it remains unknown whether it influences weight change in adult life and whether diet attenuates this association. Therefore, we investigated the association of FTO-rs9939609 with changes in weight and waist circumference (WC) during 6.8 years follow-up in a large-scale prospective study and examined whether these associations were mo...

BACKGROUND The fat mass and obesity-associated (FTO) gene is associated with obesity and type 2 diabetes mellitus. Obesity and insulin resistance are also common features of polycystic ovary syndrome (PCOS). Therefore, the FTO gene might be a candidate gene for PCOS susceptibility. The aim of the present study was to evaluate the effects of FTO gene variants on PCOS susceptibility and metabolic...

AuPd nanoparticles are formed on fluorine-doped tin oxide (FTO) by a nanosecond laser irradiation-induced dewetting process of deposited AuPd films. In particular, we analyze the effect of the surface topography of the substrate on the dewetting process and, so, on the final mean size of the formed nanoparticles. In fact, we used two supporting FTO substrates differing in the surface topography...

This work contributes to the discussion on influence of back contact electrical properties Cu2ZnSnS4 (CZTS)-based solar cells. Devices with noble metals (Au, Ag and Pt) such as FTO/ZnS/CZTS/Au, FTO/ZnS/CZTS/Pt FTO/ZnS/CZTS/Ag were investigated by means current voltage characteristic in dark (FTO = fluorine-doped tin oxide). The originality this is that all active layers (absorbing buffer layers...

OBJECTIVE To define whether the rs9939609 FTO (fat mass and obesity associated) single nucleotide polymorphism (SNP) is associated with anthropometric measurements and its modulation by educational level in a Mediterranean population. METHODS We studied 3 independent adult samples: a random sample (n = 1580) from the general population (GP), obese hospital patients (OHP) (n = 203) and elderly...

BACKGROUND Obesity is a major health problem. Although heritability is substantial, genetic mechanisms predisposing to obesity are not very well understood. We have performed a genome wide association study (GWA) for early onset (extreme) obesity. METHODOLOGY/PRINCIPAL FINDINGS a) GWA (Genome-Wide Human SNP Array 5.0 comprising 440,794 single nucleotide polymorphisms) for early onset extreme ...

Sasang constitutional medicine (SCM), a Korean tailored medicine, categorizes human beings into four types through states of physiological imbalances and responsiveness to herbal medicine. One SCM type susceptible to obesity seems sensitive to energy intake due to an imbalance toward preserving energy. Common variants of fat mass and obesity associated (FTO) and melanocortin 4 receptor (MC4R) g...

We report an inexpensive TiO2 based quantum dot solar cell (QDSSC) with improved power conversion efficiency prepared by simple techniques. Barium doped zinc sulfide has been successfully deposited on cadmium dots (QDs) successive ion layer adsorption and reaction (SILAR) technique. The is utilized as a passivation in the QDSSC, which helped better charge separation. copper (Cu2S) reduced graph...