A water balance model of Lake Victoria that can be used to assess rainfall from lake level, is derived. The model utilizes satellite estimates of rainfall directly over the lake. The model, initially derived and calibrated for the period 1956-1978, is reformulated here in such a way that all water balance terms except evaporation can be calculated from a combination of catchment rainfall and le...

Epigenetic mechanisms are involved in the pathophysiology of depressive disorders and are unique potential targets for therapeutic intervention. The acetylating agent L-acetylcarnitine (LAC), a well-tolerated drug, behaves as an antidepressant by the epigenetic regulation of type 2 metabotropic glutamate (mGlu2) receptors. It caused a rapid and long-lasting antidepressant effect in Flinders Sen...

BACKGROUND Results from cerebral proton (1)H-MR spectroscopy studies of neonates with perinatal hypoxic-ischemic injury have generally been presented as metabolite peak-area ratios, which are T1- and T2-weighted, rather than absolute metabolite concentrations. We hypothesized that compared with (1)H-MR spectroscopy peak-area ratios, calculation of absolute metabolite concentrations and relaxati...

As measured by a decreased rate of dissociation, lac repressor binds 10-times tighter to 5-bromodeoxyuridine-substituted lac operator than it does to normal lac operator. This result is obtained both in the absence and in the presence of isopropylthiogalactoside, an inducing ligand. These data are significant with regard to the mechanism of sequence-specific protein-DNA interaction, and also su...

2033. Evaluation of the FilmArray Meningitis/Encephalitis Molecular Panel in a Tertiary Care Public County Hospital Tae Hun Kim, MD; Emi Minejima, PharmD; Brad Spellberg, MD; Ira Shulman, MD; Paul Holtom, MD; Tarina Kang, MD and Susan M. Butler-Wu, PhD; Pathology, LAC-USC Medical Center, Los Angeles, California, Pharmacy, USC School of Pharmacy, Los Angeles, California, LAC-USC Medical Center, ...

Two experiments were conducted to compare the effects of enhancing dark-cutting (DC) strip loins with lactic acid (LAC) on fresh and cooked beef color, as well as sensory attributes, with nonenhanced, normal pH strip loins (CH). Strip loins, with an average ultimate pH of 6.70 ± 0.11 (Exp. 1) and 6.78 ± 0.11 (Exp. 2), were cut into 2 equal-length sections, and DC sections were randomly assigned...

BACKGROUND Peritoneal dialysis (PD) is associated with a depression of T cell function, as suggested by the impaired production of cytokines by Th cells collected from PD patients. Although treatment biocompatibility could be implicated in this immune dysfunction, it has been poorly investigated, thus far. Therefore, we undertook a study aiming to analyze the effects of different peritoneal dia...

Injected ion drift tube techniques have been used to examine the structures and to study the isomerization of Lac,+ (n = 2-90) clusters. Three families of metal-containing carbon rings ("ring Ia", "ring Ib", and "ring II"), metal-containing graphite sheets, and metallofullerenes have been resolved. Several plausible geometries with similar mobilities can be suggested for all of the ring isomers...