The concept that E2 deficiency is involved in MCT-PH may be correct; but this concept may be incorrect in human PAH. Monocrotaline is a toxin that, in male rats, reduces plasma testosterone levels by 50%, and gonadal toxicity could be the reason for reduced E2 levels. Furthermore, in the YUAN et al. [1] study, animals were not synchronised for oestrous cycle, and this may also have contributed ...

At the DAΦNE-II workshop a session was devoted to the prospects of measuring the hadronic cross section at the new DAΦNE. The session included six papers, two theoretical and four experimental ones. The theory treatises, one on the muon anomaly and the other on measuring the hadronic cross section using initial state radiation at e + e − colliders, set the background for the four experimental d...

The title compound, C17H20O2, has an E conformation about the bridging C=C bond. The cyclo-hexene ring adopts an envelope conformation with the dimethyl-substituted C atom as the flap. Its mean plane makes a dihedral angle of 7.20 (12)° with the benzene ring. In the crystal, neighbouring mol-ecules are connected via C-H⋯O hydrogen bonds, forming chains running along the a-axis direction.

The asymmetric unit of the title compound, C(11)H(16)N(2)O(2), contains two independent conformational isomers which show intra-molecular aromatic-imine O-H⋯N hydrogen bonds. In the crystal, neighboring mol-ecules are linked through inter-molecular aliphatic-aliphatic O-H⋯N, aliphatic-aromatic N-H⋯O and C-H⋯O inter-actions into hydrogen-bonded layers parallel to the ab plane.

The title compound, C21H23BrO3 [systematic name: (3E,3aS,6Z,9R,9aS,9bS)-3-(2-bromo-benzyl-idene)-9-hy-droxy-6,9-dimethyl-3,3a,4,5,7,8,9,9a-octa-hydro-azuleno[4,5-b]furan-2(9bH)-one] was prepared by the reaction of 1-bromo-2-iodo-benzene with micheliolide [systematic name: (3aS,R,9aS,9bS,Z)-9-hy-droxy-6,9-dimethyl-3-methyl-ene-3,3a,4,5,7,8,9,9a-octa-hydro-azuleno[4,5-b]furan-2(9bH)-one] under He...

The title compound, C(15)H(17)FO, was prepared directly from the aldol condensation of cyclo-octa-none with 4-fluoro-benz-aldehyde, catalysed by Pd(Ni,Ce) in the presence of trimethyl-silyl chloride. The eight-membered ring adopts a boat-chair conformation.

The asymmetric unit of the title compound, C14H11FN2O, contains two independent mol-ecules, both of which adopt the E conformation with respect to the azomethine C=N bond. The mol-ecules are non-planar, with dihedral angles of 26.92 (12) and 11.36 (11)° between the benzene and phenyl rings. In the crystal, mol-ecules are linked through N-H⋯O=C and N-H⋯N hydrogen bonds into chains along [101]. C...

The general nonlinear scalar model is studied at asymptotically low temperature near two dimensions. The low temperature expansion is renormalized and effective algorithms are derived for calculation to all orders in the renormalized expansion. The renormalization group coefftcients are calculated in the two loop approximation and topological properties of the renormalization group equations ar...