BACKGROUND Multiple imputation (MI) was developed as a method to enable valid inferences to be obtained in the presence of missing data rather than to re-create the missing values. Within the applied setting, it remains unclear how important it is that imputed values should be plausible for individual observations. One variable type for which MI may lead to implausible values is a limited-range...

BACKGROUND In the present article, we propose an alternative method for dealing with negative affectivity (NA) biases in research, while investigating the association between a deleterious psychosocial environment at work and poor mental health. First, we investigated how strong NA must be to cause an observed correlation between the independent and dependent variables. Second, we subjectively ...

OBJECTIVES The detection of patients with comorbid mental disorders is of high clinical importance. Screening instruments can be recommended for early recognition. This study investigates the discriminant validity of the Hospital Anxiety and Depression Scale (HADS), General Health Questionnaire (GHQ-12) and Patient Health Questionnaire (Brief-PHQ-D) in chronically ill patients. METHODS Two hu...

One hundred and twenty A&E Department daytime attenders were screened for psychiatric disorder in a two stage procedure. Thirty-three patients were identified as General Health Questionnaire (GHQ) 'cases' of whom 28 agreed to a psychiatric interview using the Clinical Interview Schedule. Twenty-eight GHQ 'non-cases' were also interviewed. A psychiatric diagnosis was made in 24 patients, 21 of w...

BACKGROUND Self-employed workers experience occupational stress and may suffer from various mental health disorders. AIMS To assess the mental health, substance use and risk factors for psychological distress in a sample of self-employed lawyers and pharmacists. METHODS A cross-sectional study, using self-completion postal questionnaires, of lawyers and pharmacists. The General Health Quest...

Multiple sclerosis is an unpredictable disease that can have physical, psychological, and social impacts, reducing health-related quality of life. The aim of the present study is to evaluate the sociodemographic and clinical determinants of quality of life, mental health and health representations of control in Greek patients with multiple sclerosis. A sample of 90 individuals was recruited fro...

OBJECTIVE The aim of this study was to assess the validity of the Patient Health Questionnaire depression module (PHQ-9). It has been subject to studies in medical settings, but its validity as a screening for depression in the general population is unknown. METHOD A representative population sample (2,066 subjects, 14-93 years) filled in the PHQ-9 for diagnosis [major depressive disorder, ot...

BACKGROUND The purpose of this study was to identify whether psychological stress increased as undergraduate dental students progressed through their studies from first to fifth year. Another objective was to determine if the perceived sources of stress have changed along the years. METHODS To achieve these aims, a cohort of students at the University of Jordan were followed from first to fif...

AIM The study was designed to evaluate quality of life (QOL) for Iranian patients with gastroesophageal reflux disease (GERD). BACKGROUND GERD is a common and chronic world-wide disease. Impact of GERD on QOL has been studied in many countries, but it has not been studied in Iranian population. PATIENTS AND METHODS Fifty five patients suffering from GERD and fifty five age and sex matched c...

OBJECTIVE The aim of the study was to investigate the internal consistency and screening properties of the General Health Questionnaire-12 (GHQ-12) and the Hospital Anxiety and Depression Scale (HADS) in Turkish patients with leprosy. METHODS The two screening instruments and a fully structured diagnostic interview (CIDI) were administered to 65 people drawn from all leprosy inpatient units i...