Elevated enzyme activities in plasma may at times be attributed to the presence of macro-enzymes. The macro-enzymes are often serum enzymes in complex with immunoglobulins, resulting in a greater molecular mass that cannot be filtered by renal glomeruli and are, hence, retained in the plasma. The aspartate aminotransferase (AST) can exist as a macro-enzyme, although it has been rarely reported....

Enzymatic sulfation of A'-hydroxylated arylamines by mammalian hepatic cytosol sulfotransferases (AST; EC 2.8.2.1) is an important metabolic step which generates ultimate carcinogens. The metabolic activity of AST IV, the putative ¡sozymicform of AST primarily respon sible for catalyzing /V-hydroxy-2-acetylaminofIuorene sulfation, is mod ulated during 2-acetylaminofluorene (AAF)-induced rat he...

‎in this paper‎, ‎we study a class of boundary value problem‎ ‎involving the p-laplacian oprator and singular nonlinearities‎. ‎we‎ ‎analyze the existence a critical parameter $lambda^{ast}$ such‎ ‎that the problem has least one solution for‎ ‎$lambdain(0,lambda^{ast})$ and no solution for‎ ‎$lambda>lambda^{ast}.$ we find lower bounds of critical‎ ‎parameter $lambda^{ast}$‎. ‎we use the method ...

background: hepatic steatosis due to estrogen therapyincreases the activity of inflammatory markers, particularly theactivity of tnfα which in turn induces more lipogenesis.omega-3 fatty acids are among the negative regulators of hepaticlipogenesis. objectives: in this research, the preventive effectof omega-3 fatty acids on estrogen-induced steatosis in rats wasevaluated. methods:2 mg/kg. bw/s...

OBJECTIVES The increase of serum aspartate aminotransferase (AST) is generally found in hepatic, cardiac, muscular disease and hemolytic disorders of the red blood cell (RBC). The elevation of its activity is suspected in pathological conditions of these organs. However, instances without any of those conditions rarely exist. METHODS The experimental samples were obtained from a normal person...

In vitro supplementation with the active form of vitamin B6, pyridoxal-phosphate (PLP), increases measurements of both serum aminotransferase enzymes, L-aspartate: 2-oxoglutarate amino transferase, EC 2.6.1.1 (AST) and L-alanine: 2-oxoglutarate aminotransferase, EC 2.6.1.2 (ALT). The plasma PLP level in normal individuals clearly relates inversely to the degree of stimulation of serum AST and A...

Purpose. By examining the prescribing patterns and inappropriate use of acid suppressive therapy (AST) during hospitalization and at discharge we sought to identify the risk factors associated with such practices. Methods. In this retrospective observational study, inpatient records were reviewed from January 2011 to December 2013. Treatment with AST was considered appropriate if the patient ha...

BACKGROUND Removal of uraemic toxins by AST-120 (Kremezin(®)) decreases the progression of chronic kidney disease by reducing oxidative stress. We performed this study to evaluate whether AST-120 has a similar effect on progression of cyclosporine (CsA)-induced renal injury. METHODS Two separate studies were performed in adult Sprague-Dawley rats. First, AST-120 was administered with CsA (15 ...

The paper defines an annotated su x tree (AST) a data structure used to calculate and store the frequencies of all the fragments of the given string or a collection of strings. The AST is associated with a string to text scoring, which takes all fuzzy matches into account. We show how the AST and the AST scoring can be used for Natural Language Processing tasks.

Background: Over the last few decades, rates of active transport (AST) among school age children have decreased as rates of child obesity have increased. Thus, it has been proposed that increasing AST in this population would help stem the tide of child obesity and improve child health. The evidence for the capacity of AST to reduce child obesity, however, is mixed. Purpose: To examine the asso...