نتایج جستجو برای: هموگلوبین a1
تعداد نتایج: 25563 فیلتر نتایج به سال:
BACKGROUND Both the A1- and A3-adenosine receptors (ARs) have been implicated in mediating the cardioprotective effects of adenosine. Paradoxically, overexpression of both A1-AR and A3-AR is associated with changes in the cardiac phenotype. To evaluate the temporal relationship between AR signaling and cardiac remodeling, we studied the effects of controlled overexpression of the A1-AR using a ...
The heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) functions in the packaging of nascent RNA polymerase II transcripts and participates in a variety of nuclear and cytoplasmic processes that modulate gene expression. The RNA binding characteristics of hnRNP A1 suggest that it can modulate the expression of specific genes, but little is known about its possible targets in vivo. In this ar...
We have isolated and characterized the human homolog of the rat largest urea transporter of the UT-A family (hUT-A1). The 4.2-kb hUT-A1 cDNA encodes a 920-amino acid peptide, which is 89% identical to the rat UT-A1 protein. By Northern hybridization, hUT-A1 expression is detected in the human inner medulla as a approximately 4.4-kb mRNA transcript. By Western analysis, hUT-A1 is identified as a...
Let AkAk−1⋯A1 be the product of some nonnegative 2-by-2 matrices. In general, its elements are hard to evaluate. Under conditions, we show that ∀i,j∈{1,2}, (AkAk−1⋯A1)i,j∼cϱ(Ak)ϱ(Ak−1)⋯ϱ(A1) as k→∞, where ϱ(An) is spectral radius matrix An and c∈(0,∞) constant. Consequently, can estimated. As applications, consider maxima certain excursions (2,1) (1,2) random walks with asymptotically zero drif...
to the complex plane. We show that for fixed s 6= n/2, the function Zn(s; a1, . . . , an), as a function of (a1, . . . , an) ∈ (R) with fixed Qn i=1 ai, has a unique minimum at the point a1 = . . . = an. When Pn i=1 ci is fixed, the function (c1, . . . , cn) 7→ Zn (s; e c1 , . . . , en ) can be shown to be a convex function of any (n−1) of the variables {c1, . . . , cn}. These results are then ...
The Money Changing Problem is as follows: Let a1 < a2 < · · · < ak be fixed positive integers with gcd(a1, . . . , ak) = 1. Given some integer n, are there non-negative integers x1, . . . , xk such that ∑ i aixi = n? The Frobenius number g(a1, . . . , ak) is the largest integer n such that the above problem has no decomposition x1, . . . , xk. There exist algorithms that, for fixed k, compute t...
FcepsilonRI-activation-induced survival of mast cells is dependent on the expression and function of the prosurvival protein A1. The expression of A1 in lymphocytes and monocytes has previously been described to be transcriptionally regulated by NF-kappaB. Here we demonstrate that the expression of A1 in mast cells is not dependent on NF-kappaB but that NFAT plays a crucial role. FcepsilonRI-in...
BACKGROUND HBV subgenotype A1 is the dominant genotype A strain in Africa, with molecular characteristics differentiating it from A2, which prevails elsewhere. Outside Africa, A1 is confined to areas with migration history from Africa, including India and Latin America. The aim of this study was to reconstruct A1 phylogeny on a spatial scale in order to determine whether A1 can be used to track...
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