Fipronil is a commonly used insecticide that has been shown to have environmental and human health risks. The current standard methods of detection for fipronil and its metabolites, such as GC-MS, are time consuming and labor intensive. In this study, a variant of systematic evolution of ligands by exponential enrichment (SELEX), was utilized to identify the first single-stranded DNA (ssDNA) mo...

Small bowel tumors and other rare intestinal disorders are often exceedingly difficult to identify. Even cutting-edge technologies, such as push enteroscopy and capsule endoscopy, can fail to determine the cause of a patient's symptoms. At our institution magnetic resonance enterography (MRE) has become an increasingly reliable tool in the difficult-to-diagnose or difficult-to-monitor patient. ...

The Magnitude of Relative Error, MRE, is probably the most widely used basic metric in common evaluation criteria, e.g. MMRE and PRED, to assess the performance of software prediction models. The implicit rationale of using a relative error measure, rather than an absolute one, is to have a measure that is independent of scale. In this paper, we investigate if this implicit claim holds true usi...

A modular application of the integration by fractional expansion method for evaluating Feynman diagrams is extended to diagrams that contain loop triangle subdiagrams in their geometry. The technique is based in the replacement of this module or subdiagram by its corresponding multiregion expansion (MRE), which in turn is obtained from Schwinger’s parametric representation of the diagram. The r...

Heritable endobacteria, which are transmitted from one host generation to the next, are subjected to evolutionary forces that are different from those experienced by free-living bacteria. In particular, they suffer consequences of Muller's ratchet, a mechanism that leads to extinction of small asexual populations due to fixation of slightly deleterious mutations combined with the random loss of...

Iron-inducible transcription of a malic enzyme gene (also reputed to be ap65-1) in Trichomonas vaginalis was previously shown to involve a Myb1 repressor and a Myb2 activator, each of which may preferentially select two closely spaced promoter sites, MRE-1/MRE-2r, which comprises overlapping promoter elements, and MRE-2f. In the present study, an iron-inducible approximately 32-kDa Myb3 nuclear...

The dynamics of the sol/gel phase transition in agarose was analyzed with magnetic resonance elastography (MRE) and diffusion-weighted imaging, providing complementary information on a microstructural as well as on a macroscopic spatial scale. In thermal equilibrium, the diffusion coefficient of agarose is linearly correlated with temperature, independent of the sol/gel phase transition. In lar...

PURPOSE To assess if higher-resolution magnetic resonance elastography (MRE) is a technique that can measure the in vivo mechanical properties of brain tissue and is sensitive to early signatures of brain tissue degradation in patients with clinically isolated syndrome (CIS). MATERIALS AND METHODS Seventeen patients with CIS and 33 controls were investigated by MRE with a 3T MRI scanner. Full...

Cerebral viscoelastic constants can be measured in a noninvasive, image-based way by magnetic resonance elastography (MRE) for the detection of neurological disorders. However, MRE brain maps of viscoelastic constants are still limited by low spatial resolution. Here we introduce three-dimensional multifrequency MRE of the brain combined with a novel reconstruction algorithm based on a model-fr...

Symbiosis, defined as prolonged and close association of two or more different organisms, is a major driving force for expansion of biological diversity from genes to ecosystems. In the most intimate form, the symbiont lives inside the cells of its host, is heritable, and the two parties could no longer survive independently. Such heritable endosymbiosis blurs the line of what constitutes an in...