nitric oxide (no) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. recent evidences suggest that no may act as an endocrine molecule. the aim of this review is considering available literature on endocrine roles of no and/or its metabolites, i.e. nitrite and nitrate. existing data suggest the idea that no is a hormone that after production i...

background: nitrate and nitrite compounds are considered as groundwater’s contamination factors, which in recent years, their densities have been growing in these resources. this study was conducted aiming to measure nitrate and nitrite density in drinking water wells in villages around the industrial estate, city of orumieh, and to compare them to the approved standards. methods: this was a de...

a simple and rapid spectrophotometric method for the determination of nitrite in water and soil preparation samples has been developed. determination of nitrite is based on diazotization of p-nitro aniline with nitrite and subsequent coupling with 4-amino-3-hydroxynaphthalene-1-sulfonic acid in hydrochloric acid. the factors affecting the reaction i.e. concentration of p-nitro aniline, concentr...

introduction: renin angiotensin system has an important role in blood pressure and renal functions. active angiotensin-converting enzyme 2 converts angiotensin i into angiotensin-(1-7) which is a vasodilator hormone and interacts with nitric oxide changes as well as other angiotensin ii receptors. in this study we evaluated the role of mas receptor antagonist (a779) and renal perfusion pressure...

Water extract of respirable particulate matter (RPM) was analyzed by Ion chromatography technique to investigate the presence of nitrite (NO2) as secondary aerosol in ambient environment. The nitrite particulates undergo photo hydroxyl radical reaction in environment produce nitrous acid, which reacts with metal and absorbs on RPM as water-soluble metal salt. The mean concentration of nitrite w...

Recent research suggests the vivid possibility of using nitrite therapy against various pathological conditions. Moreover, chronic nitrite therapy offers protection against ischemia and augments endothelial cell proliferation through unknown mechanisms. Nitrite-mediated augmentation in the number of circulating neutrophils has also been reported; however, the exact mechanism is not known. In th...

Recent research suggest that anoxia-tolerant fish transfer extracellular nitrite into the tissues, where it is used for nitric oxide (NO) generation, iron-nitrosylation, and S-nitrosation of proteins, as part of the cytoprotective response toward prolonged hypoxia and subsequent reoxygenation. We hypothesized that crucian carp take up ambient nitrite and use it as a source of cellular NO availa...

BACKGROUND Estimation of nitrate and nitrite concentrations of milk sources may provide insight into potential health risks and benefits of these food sources for infants, children, and adults. The World Health Organization and American Academy of Pediatrics recommends exclusive consumption of human milk for the first 6 months of life. Human milk is known to confer significant nutritional and i...

The biological nitrogen cycle involves step-wise reduction of nitrogen oxides to ammonium salts and oxidation of ammonia back to nitrites and nitrates by plants and bacteria. Neither process has been thought to have relevance to mammalian physiology; however in recent years the salivary bacterial reduction of nitrate to nitrite has been recognized as an important metabolic conversion in humans....