Background: Boron Neutron Capture Therapy (BNCT) is an emerging radiotherapy. There are ongoing efforts to develop a Canadian accelerator-based BNCT center. However, it remains unclear how radiation oncologists (RO), medical physicists (MP), and their trainees perceive its impact on oncology as discipline. Methods: A survey was created explore the knowledge of BNCT, clinical role, support for r...

Boron neutron capture therapy (BNCT) involves administration of a boron compound followed by neutron irradiation of the target organ. The boron atom captures a neutron, which results in the release of densely ionizing helium and lithium ions that are highly damaging and usually lethal to cells within their combined track length of approximately 12 microns. Prior to Phase I clinical trials for p...

PURPOSE To analyze the clinical data, MRI, pathological diagnosis, treatment and long-term effects of benign notochordal cell tumor (BNCT), a newly described novel spine tumor. METHODS We retrospectively studied 11 patients' clinical data of the above. RESULTS The ratio of males to females was 4:7, and the average age was 49.2 years (range, 18-74 years). Cervical vertebra (5; 38.5%) and tho...

Boron Neutron Capture Therapy (BNCT) is a binary cancer therapy particularly well-suited to treating aggressive tumours that exhibit a high degree of infiltration of the surrounding healthy tissue. Such tumours, for example of the brain and lung, provide some of the most challenging problems in oncology. The first element of the therapy is boron-10 which is preferentially introduced into the ca...

Within our activities on accelerator-based boron neutron capture therapy (BNCT) carried out at the Tandar Laboratory (Comisión Nacional de Energı́a Atómica, Argentina) we present here the study and design of a tomographic imaging system for the measurement of the spatial distribution of the absorbed dose during a BNCT session. The 10B(n,α)7Li boron neutron capture reaction produces a 478 keV gam...

Introduction: The Monte Carlo simulation is used to enhance reliability in the experiments related to nuclear instruments. in addition, that is used to calculate the different components of the neutron and gamma ray fluxes in boron neutron capture therapy(BNCT) and neutron capture (NCT)applications. BNCT is one of the methods in radiotherapy, that is used the neutron beam for ki...

Reverse-biased silicon p-n junction arrays have been proposed as microdosimetry detectors. The tissue equivalence of such detectors in boron neutron capture therapy (BNCT) is discussed. A comparison of the range-energy relationships of H, He, C, and Li ions in tissue (ICRU-muscle) and silicon is given. A simple geometrical scaling (approximately 0.63) of linear dimensions is required to convert...

Boron neutron capture therapy (BNCT) is a promising cancer treatment modality that combines targeted boron agents and irradiation to selectively destroy tumor cells. In mainland China, the clinical implementation of BNCT has made certain progress, primarily driven by development compact source devices. The availability, ease operation, cost-effectiveness offered these sources make more accessib...