introduction: long-term levodopa treatment of parkinson’s disease (pd) is frequently complicated by spontaneously occurring involuntary muscle movements called dyskinesia. the exact pathological mechanism of this complication has not yet been elucidated. we have previously demonstrated that in pd patients the vulnerability to develop peripheral but not orofacial dyskinesia is associated with th...

Introduction: Neuroinflammation may play as an important risk factor in progressive degeneration of dopaminergic cells. Antioxidants have protective effects against free radicalsinduced neural damage in Parkinson’s disease (PD). In the present study, we examined the effects of ellagic acid (EA) on locomotion and neuroinflammatory biomarkers in a rat model of PD induced by 6-hydroxidopamin...

Background: There is little information about the survival rate of pediatric peritoneal dialysis (PD) patients and its risk factors. Therefore, the aim of the present study was to assess survival rate and its risk factors in Iranian children undergoing PD. ...

   Objectives: The present study aimed at investigating the relationship between Dysphonia Severity Index (DSI) and disease speech and voice severity of Parkinson disease (PD) patients. Method. This study was a cross-sectional ones, carried out on 45 PD patients with the age range of 50 to 75 years, who were randomly selected. The Hoehn and Yahr Scale (H.Y Scale) was employed to measure the le...

The programmed death-1 (PD-1) molecule is involved in peripheral tolerance and in the immune escape mechanisms during chronic viral infections and cancer. PD-1 interacts with two ligands, PD-L1 and PD-L2. We have investigated the molecular mechanisms of PD-1 interactions with its ligands by surface plasmon resonance and cell surface binding as well as the ability of the two ligands to compete f...

به منظور ساخت، راه‌اندازی و عیب‌یابی مقدماتی چشمه پنینگ داخلی سیکلوترون 10IRANCYC، یک مگنت الکتریکی دوقطبی با میدان مغناطیسی در حد امکان مشابه مرکز مذکور طراحی ساخته شد. این الکترومگنت که دانشکده فیزیک دانشگاه تهران شد، قادر است بزرگی 7000 گوس را محل استقرار (منطقه‌­ای شعاع 15 میلی‌متر مگنت) آسانی بدون نیاز خنک‌سازی تأمین کند. دست‌­یابی 1/1 تسلا نیز استفاده از برای مدت چند دقیقه امکان‌­پذیر است...

in this study, porcelain bond strength to three different alloys of gold-base, pd-ag and base-metal were compared and the effect of repeated porcelain sintering on bond strength was evaluated. the obtained results showed best bond strength of porcelain with gold-base alloy. pd-ag and base-metal alloys showed less strength respectively. during repeated sintering of porcelain, bond strength has n...

In this paper, stabilization of the structural system against earthquake is presented. Because the conventional PD controller is popular and simple in design, our controller is based on PD controller. The main problem of such a controller is its inability to produce desired response and instability against variations in the properties of the structural system. To obviate this issue, the neu...

The catalytic acvtivity of dimeric and monomeric ortho-palladated complexes [Pd{C6H2(CH2NH2-(OMe)2,3,4}(µ-Cl)]2)2) and [Pd{C6H2(CH2NH2-(OMe)2,3,4}Cl(PPh3)](3), was investigated in Heck cross-coupling reaction. These complexes are more active and efficient catalysts for Heck cross-coupling reaction. The palladium complexes 2 and 3 is employed in the Heck cross-coupling reaction between styrene a...