Calcific Aortic Valve Disease: Where Are We Now? Calcific aortic valve disease (CAVD) is the most common valvular heart disease in the aging population of the developed world with projected disease burden expected to increase from 2.5 million in 2000 to 4.5 million in 2030. In CAVD, the leaflets become thick, stiff, scarred, and calcified, often covered with nodules on the surface facing the ao...

AIM Patients with severe aortic stenosis (AS) may have bleeding episodes due to the loss of high-molecular-weight (HMW) von Willebrand factor multimers (VWFMs). The absence of HMW-VWFMs and bleeding tendency are usually corrected after aortic valve replacement (AVR). To investigate the process of VWFM recovery and symptoms in patients with severe AS, we analyzed changes in VWF antigen (VWF:Ag),...

The aim of this study was to assess the validity and test-retest reliability of Thermovision Technique of Dry Needling (TTDN) for the gluteus minimus muscle. TTDN is a new thermography approach used to support trigger points (TrPs) diagnostic criteria by presence of short-term vasomotor reactions occurring in the area where TrPs refer pain. Method. Thirty chronic sciatica patients (n=15 TrP-pos...

Of 415 patients, 200 undergoing aortic valve replacement (AVR) and 215 undergoing AVR in combination with myocardial revascularization [coronary artery bypass grafting (CABG)], had complete preoperative health-related quality of life (HRQOL) data. From this group, 224 patients had a follow-up of one year. To assess HRQOL, the EuroQol instrument was used. The EQ-5D index score was calculated, ba...

To evaluate the diagnostic utility and cost-effectiveness of Doppler echocardiography in adults with symptomatic aortic stenosis, we performed a prospective study in which the need for aortic valve replacement (AVR) was the outcome event. The total sample consisted of 103 adults (mean age, 69 years) undergoing cardiac catheterization for suspected aortic stenosis. Twenty-six patients (25%) were...

Recent anatomic findings indicate that in the upper inner medulla of the rodent kidney, tubules, and vessels are organized around clusters of collecting ducts (CDs). Within CD clusters, CDs and some of the ascending vasa recta (AVR) and ascending thin limbs (ATLs), when viewed in transverse sections, form interstitial nodal spaces, which are arrayed at structured intervals throughout the inner ...

Background Sutureless aortic valve replacement (SU-AVR) has been developed as an alternative surgical treatment for patients with symptomatic severe aortic stenosis (AS). The aim of this study was to evaluate the clinical outcomes of SU-AVR through an assessment of hemodynamic performance and safety. Methods From December 2014 to June 2016, a total of 12 consecutive patients with severe AS un...

The present work presents teaching–learning based optimization (TLBO) algorithm as an optimization technique in the area of tuning of the classical controller installed in automatic voltage regulator (AVR). The proposed TLBO algorithm is applied with an aim to find out the optimum value of proportional integral derivative (PID) controller gains with first order low pass filter installed in the ...

OBJECTIVES There is a current trend towards the use of bioprosthetic aortic valves in the aortic position in young patients, but there is limited information on durability beyond the first decade. The Hancock II bioprosthesis has been reported to have excellent durability in patients ≥ 60 years of age. This study examines the long-term durability of the Hancock II bioprosthesis in the aortic po...