HERPES SIMPLEX VIRUS TYPE 2 (HSV-2) seroprevalence has increased by 32% in the last decade. Overall, HSV-2 seroprevalence is 22% in the general US adult population, and in some populations, such as sexually transmitted disease (STD) clinic attendees, seroprevalence varies between 30% and 50%. Concomitant with this increase in genital herpes has been an increase in reported cases of neonatal her...

Neuron Immediate Early Publication Copyright ©2004 by Cell Press Published Online April 15, 2004 DOI: 10.1016/S0896-627304001795 Conserved Roles for Slit and Robo Proteins in Midline Commissural Axon Guidance Hua Long, Christelle Sabatier, Le Ma, Andrew Plump, Wenlin Yuan, David M. Ornitz, Atsushi Tamada, Fujio Murakami, Corey S. Goodman, and Marc Tessier-Lavigne* Howard Hughes Medical Institut...

Valentin Stanev, 2 Corey Oses, 4 A. Gilad Kusne, 5 Efrain Rodriguez, 2 Johnpierre Paglione, 2 Stefano Curtarolo, 4, 8 and Ichiro Takeuchi 2 Department of Materials Science and Engineering, University of Maryland, College Park, MD 20742-4111, USA Center for Nanophysics and Advanced Materials, University of Maryland, College Park, Maryland 20742, USA Department of Mechanical Engineering and Mater...

An electrochemical version of the Corey-Winter reaction was developed giving excellent results in aqueous methanol media (MeOH/H2O (80:20) with AcOH/AcONa buffer 0.5 M as supporting electrolyte), using a reticulated vitreous carbon as cathode in a divided cell. The electrochemical version is much more environmentally friendly than the classical reaction, where a large excess of trialkyl phosphi...

The first demonstration of transformation (Griffith, 1928) was concerned with type-specific capsular polysaccharides of pneumococci. Such transformations of capsular types usually are accompanied by a change in colony type since most investigators have studied transformation of R cells which produce little or no capsular material. Coiacomitant transformation of capsular and colony type has been...

هدف این پژوهش، طراحی مدل بهینه‌سازی دوسطحی برای زنجیره تأمین است؛ به‌طوری‌که تصمیم‌گیری غیرمتمرکز کمّی و کیفی را در سطوح استراتژی تاکتیکی ادغام کند. کارخانه تولیدی نقش تصمیم‌گیرنده سطح بالا با ارائه تخفیف مقداری، به دنبال ترغیب مشتریان سفارش خرید بیشتر است. پایین، به‌عنوان پایین تمایل دارند مقادیر از طریق مشارکتی، مقیاس اقتصادی دست یابند. یکی نخستین پژوهش­هایی است که یافتن راه‌حل‌های بهینه مسئله...

Twelve years after their discovery in plants, prohibitins (PHBs) have retained their status as some of the most enigmatic mitochondrial proteins. Although the original hypothesis that PHBs act as negative cell cycle regulators has lost its impetus in plants, the essential molecular function(s) PHB complexes perform in the inner mitochondrial membrane are now beginning to be understood. We revie...

The hemlock woolly adelgid (HWA), Adelges tsugae Annand, has been recognized as a major pest of eastern hemlock, Tsuga canadensis Carriere, and the less frequently encountered Carolina hemlock, T. caroliniana Engelm. Biological control is seen as the most promising method of largescale control of HWA, however, there is currently no effective method for estimating population levels of biological...

Here we report the first experimental detection of the Cs symmetric nitroformyl radical, OCNO(X A00) in a nitrogen–carbon dioxide matrix at 10 K using a Fourier transform infrared spectrometer (FTIR). The n1 vibrational frequency was observed at 2113 cm . This assignment was confirmed by follow-up experiments using isotopically labeled reactant molecules (N, O, C). To synthesize this radical, w...

In a preliminary communication last year' we stated that there are only two helical configurations of polypeptide chains in which the residues are all equivalent and intramolecular hydrogen bonds are formed, and in which the interatomic distances, bond angles, and other structural features, especially the coplanarity of the conjugated amide system, are as required by earlier work in these Labor...