A disease can be defined as an abnormal anatomy (pathology) and/or function (physiology) that may cause harm to the body. In clinical benign prostatic hyperplasis (BPH), the abnormal anatomy is prostate adenoma/adenomata, resulting in a varying degree of benign prostatic obstruction (BPO) that may cause harm to the bladder or kidneys. Thus clinical BPH can be defined as such and be differentiat...

Quantitative in vitro studies of antioxidant activities have been performed under aerobic conditions. However, since the biological system has lower oxygen tension, the effectiveness of antioxidants may be considerably different in vivo. alpha-Tocopherol, in vivo the most active tocopherol, is a very poor antioxidant in vitro. To clarify these points, the radical-scavenging activities of vitami...

Tissue-resident memory T (TRM) cells have emerged as key players and potential immunotherapeutic targets in antitumor immunity. However, the study of TRM within TME has been hampered by a lack adequate tumor models. Cell lines injected subcutaneously do not contain same biological cues tumors arising from dermis epidermis, while most other models known tumor-specific antigen to track immune res...

This study compared the efficacy of 70- and 120-w 2-µm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with symptomatic BPO and prostatic enlargement (≥60 ml) who underwent either 70-w (n=44) or 120-w ThuVEP (n=40) non-randomly was carried out. Patient demographics and perioperative and 12-month fol...

Progression of benign tumors to malignant cancer is critical since can cerous lesions are capable of metastatic spread and eventually causing death. Inhibitors of the conversion process, therefore, would likely be useful as cancer chemopreventive agents. In this study, we assessed the protective effect of topical application of a polyphenolic fraction isolated from green tea (GTP) against spont...