نتایج جستجو برای: مدل های ریاضی بیماری wnv
تعداد نتایج: 527835 فیلتر نتایج به سال:
The northern Great Plains (NGP) of the United States has been a hotspot of West Nile virus (WNV) incidence since 2002. Mosquito ecology and the transmission of vector-borne disease are influenced by multiple environmental factors, and climatic variability is an important driver of inter-annual variation in WNV transmission risk. This study applied multiple environmental predictors including lan...
BACKGROUND West Nile virus (WNV) is a growing threat to public health and a greater understanding of the immune response raised against WNV is important for the development of prophylactic and therapeutic strategies. METHODOLOGY/PRINCIPAL FINDINGS In a reverse-immunology approach, we used bioinformatics methods to predict WNV-specific CD8(+) T cell epitopes and selected a set of peptides that...
Differential host responses may be critical determinants of distinct pathologies of West Nile virus (WNV) NY99 (pathogenic) and WNV Eg101 (non-pathogenic) strains. We employed RNA-seq technology to analyze global differential gene expression in WNV-infected mice brain and to identify the host cellular factors leading to lethal encephalitis. We identified 1,400 and 278 transcripts, which were di...
Dra. Maritza Pupo-Antúnez – Novia del Mediodía Km 6 1⁄2 La Lisa, Habana, Cuba. E-mail: [email protected] West Nile virus (WNV) is a flavivirus grouped in Japanese encephalitis virus serogroup due to serological antigenic characteristics. WNV is transmitted to humans through the bite of infected mosquitoes which acquire the virus after feeding on vertebrate amplifying hosts, mainly birds. WNV is ...
The mosquito-borne West Nile virus (WNV) causes human and animal disease with outbreaks in several parts of the world including North America, the Mediterranean countries, Central and East Europe, the Middle East, and Africa. Particularly in elderly people and individuals with an impaired immune system, infection with WNV can progress into a serious neuroinvasive disease. Currently, no treatmen...
Infections of the central nervous system (CNS) with cytopathic viruses require efficient T cell responses to promote viral clearance, limit immunopathology, and enhance survival. We found that IL-1R1 is critical for effector T cell reactivation and limits inflammation within the CNS during murine West Nile virus (WNV) encephalitis. WNV-infected IL-1R1(-/-) mice display intact adaptive immunity ...
روند افزایشی خسارت های جانی و مالی ناشی از جاری شدن سیلاب، مهندسین را بر آن داشته است تا با اتکاء به ابزار مدرنی نظیر مدل های پیشرفته ریاضی، چاره ای نو جهت کنترل و مدیریت این پدیده بیأندیشند. امروزه مبارزه با سیل از طریق روش های مدیریت غیرسازه ای در حوزه های آبخیز و در مسیر رودخانه ها، مورد توجه فراوان قرار گرفته است که،ازجمله اقدامات مدیریتی که می تواند نقش به سزایی درکاهش خسارات ناشی ازوقوع س...
A human outbreak of West Nile virus (WNV) infection caused by WNV lineage 2 is ongoing in northern Italy. Analysis of six WNV genome sequences obtained from clinical specimens demonstrated similarities with strains circulating in central Europe and Greece and the presence of unique amino acid changes that identify a new viral strain. In addition, WNV lineage 1 Livenza, responsible for a large o...
West Nile virus (WNV) has become the principal cause of viral encephalitis in North America since its introduction in New York in 1999. This emerging virus is transmitted to humans via the bite of an infected mosquito. While there have been several candidates in clinical trials, there are no approved vaccines or WNV-specific therapies for the treatment of WNV disease in humans. From studies wit...
A West Nile virus (WNV) surveillance network including sentinel chickens was deployed in Thessaloniki county, Greece, from May to July 2011. For the first time in summer 2011, a chicken WNV isolate from 6 July was molecularly identified. The partial NS3 sequence was identical to that of the Nea Santa-Greece-2010 WNV lineage 2, detected in central Macedonia in 2010. This suggests that WNV is act...
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