Electrospray ionization with in-source collisionally induced dissociation has been used to probe the gas phase stability of an oligonucleotide duplex and its complexes with some minor groove binding drugs. On the basis of the arguments developed in detail by Drahos et al. (J. Mass Spectrom. 1999; 34:1373), this type of experiment can also be described as 'thermal denaturation in the gas phase'....

The 9/11 suicide attacks in New York, Washington, D.C., and Pennsylvania, triggered a number of security responses both in the United States of America and other Countries in the World. Kenya, which is an ally and a close partner to North America and Europe, was not left behind. While many states had been parties to numerous terrorism conventions, their response in implementing them had been sl...

Thermal barrier coatings (TBCs), consisting of physical vapor deposited (PVD) partially stabilized zir-conia (PSZ, 8 wt. %Y203) and a diffusion aluminide bond coat, were characterized as a function of time after oxidative isothermal heat treatment at 1373 K in air. The experimental characterizations was conducted by X-ray diffraction analysis and scanning electron microscopy (SEM) with energy-d...

OBJECTIVE To further refine our understanding of impulsivity, obsessions, and compulsions in anorexia nervosa (AN) by isolating which behaviours--binge eating, purging, or both--are associated with these features. METHODS We conducted regression analyses with binge eating, purging, and the interaction of binge eating with purging as individual predictors of scores for impulsivity, obsessions,...

In this paper, the interdiffusivities in fcc Co-Ni alloys at 1373 K due to different types of diffusion couple experiments were firstly re-calculated via the unified Wagner method based on the measured composition profiles. Their maximum difference due to different approaches for diffusion couple preparation was found to be larger than one order of magnitude. Then, a comprehensive analysis on t...

Blood vessels express 3 isoforms of superoxide dismutase (SOD): cytosolic or copper-zinc SOD (CuZn-SOD), manganese SOD (Mn-SOD) localized in mitochondria, and an extracellular form of CuZn-SOD (EC-SOD). Because there are no selective pharmacological inhibitors of individual SOD isoforms, the functional importance of the different SODs has been difficult to define. Recent molecular approaches, p...

We present a novel method for low noise, high-speed, real-time spectroscopy to monitor molecular absorption spectra. The system is based on a rapidly swept, narrowband CW Fourier-domain mode-locked (FDML) laser source for spectral encoding in time and an optically time-multiplexed split-pulse data acquisition system for improved noise performance and sensitivity. An acquisition speed of ~100 kH...

We present ‘BYTe’, a comprehensive ‘hot’ line list for the ro-vibrational transitions of ammonia, NH3, in its ground electronic state. This line list has been computed variationally using the program suite TROVE, a new spectroscopically determined potential energy surface and an ab initio dipole moment surface. BYTe, is designed to be used at all temperatures up to 1500 K. It comprises 1138 323...