OBJECTIVE Somatotropinomae are classified as densely and sparsely granulated adenomae, which typically exhibit a perinuclear pattern (PP) and a dot pattern (DP) in cytokeratin (CK) immunostaining respectively. Some exhibit a mixed pattern (MP). We studied the relationship between these somatotropinoma subtypes and their clinico-pathological features. METHODS The study population consisted of ...

BACKGROUND Few studies have addressed the influence of dietary patterns (DP) during adolescence on the amount of body fat in early adulthood. OBJECTIVE To analyze the associations between DP tracking and changes in the period between 15 and 18 years of age and the percentage of body fat (%BF) at age 18 years. METHODS We used data from 3,823 members of the 1993 Pelotas (Brazil) birth cohort....

TO THE EDITOR Although keratinocytes are the primary constituents of the hair follicle and generate the hair shaft, mesenchymal cells also have important functions. These include the follicular dermal papilla (DP) and the connective tissue sheath or dermal sheath (CTS). The DP is embedded in the hair bulb during the anagen phase and forms a compact ball during the telogen phase, whereas CTS cel...

Objetivo: aferir os custos diretos médios de curativos úlceras vasculogênicas realizados por profissionais enfermagem em pacientes atendidos uma Unidade Tratamento Integral Ferida. Método: Pesquisa quantitativa, exploratório-descritiva, conduzida numa Ferida, localizada Vitória da Conquista, Bahia - Brasil, março, agosto e setembro 2020. Calcularam-se multiplicando-se o tempo despendido (cronom...

The Gaussian mechanism (GM) represents a universally employed tool for achieving differential privacy (DP), and large body of work has been devoted to its analysis. We argue that the three prevailing interpretations GM, namely epsilon/delta-DP, f-DP Rényi DP can be expressed by using single parameter psi, which we term sensitivity index. Psi uniquely characterises GM properties encapsulating tw...

PURPOSE Recent insights regarding the pathogenesis of malignant pleural mesothelioma (MPM) provide new opportunities for targeted molecular therapies for this highly lethal disease. The present study was undertaken to examine the effects of the histone deacetylase inhibitor, Depsipeptide (DP) FK228, in conjunction with the cyclin-dependent kinase inhibitor, Flavopiridol (FLA), in cultured MPM c...

BACKGROUND Assessment of color disc photograph (C-DP) is affected by image quality, which decreases the ability to detect glaucoma. High-dynamic-range (HDR) imaging provides a greater range of luminosity. Therefore, the objective of this study was to evaluate the capability of ophthalmology residents to detect glaucoma using HDR-concept disc photography (HDR-DP) compared to C-DP. DESIGN Cross...

Previous studies have revealed that HIV-infected individuals possess circulating CD4(+)CD8(+) double-positive (DP) T cells specific for HIV Ags. In the present study, we analyzed the proliferation and functional profile of circulating DP T cells from 30 acutely HIV-infected individuals and 10 chronically HIV-infected viral controllers. The acutely infected group had DP T cells that showed more ...