In the 1996-1997 cholera epidemic in Guinea-Bissau, surveillance for antimicrobial resistance showed the emergence of a multidrug-resistant strain of Vibrio cholerae O1 during the course of the epidemic. The strain was resistant to ampicillin, erythromycin, tetracycline, furazolidone, aminoglycosides, trimethoprim, and sulfamethoxazole. Concomitant with the emergence of this strain, we observed...

Background and objectives: Halo interference around antibiogram disc is one of the problems seen in Agar media. This study aimed at applying graded plate method to reduce this problem. Material and Methods: Forty-eight millimeter plates, before putting disc, were graded and the location of discs was determined. Instead of full disc, we used half-disc and then compared the haloe interference, ba...

Data are available such that choice of Helicobacter pylori therapy for an individual patient can be reliably predicted. Here, treatment success is defined as a cure rate of 90% or greater. Treatment outcome in a population or a patient can be calculated based on the effectiveness of a regimen for infections with susceptible and with resistant strains coupled with the knowledge of the prevalence...

A prescription audit was carried out among the outpatient attendees of 31 secondary level hospitals under Maharashtra Health Systems Development Project. Use of drugs and cost of treatment of diarrhoea were studied using the prescriptions for diarrhoea collected for the prescription audit. Average number of drugs prescribed per prescription for treatment of diarrhoea was 3.7. It was higher than...

The present study was conducted to know the prevalence of Salmonella and E.coli serovars in pigs at different localities of Andhra Pradesh as non typhoidal Salmonella strains and E.coli are important causes of reportable food borne infection. Among 101 faecal samples screened six isolates of Salmonella ie. S. derby (3) , S.typhimurium (2) and S.typhisuis (1) and twenty isolates of E.coli viz. 0...

Currently, a standard third-line therapy for Helicobacter pylori (H. pylori) eradication remains to be established. Quinolones show good oral absorption, no major side effects, and marked activity against H. pylori. Several authors have studied quinolone-based third-line therapy and reported encouraging results, with the reported H. pylori cure rates ranging from 60% to 84%. Resistance to quino...