ATP-dependent chromatin remodeling complexes, such as SWI/SNF, are required for transcriptional activation of specific genes and are believed to be recruited to gene promoters by direct interaction with DNA binding transcription factors. However, we report here that recruitment of SWI/SNF to target genes of estrogen receptor alpha (ERalpha) requires the previously described nuclear receptor coa...

Susceptibility-weighted imaging (SWI) consists of using both magnitude and phase images from a high-resolution, three-dimensional, fully velocity compensated gradient-echo sequence. Postprocessing is applied to the magnitude image by means of a phase mask to increase the conspicuity of the veins and other sources of susceptibility effects. This article gives a background of the SWI technique an...

Soil moisture is a key driver of many meteorological, hydrological and climatological processes. Satellite remote sensing using radar sensors facilitates its global monitoring and depicts valuable input to meteorological models, agricultural management and flood prediction. However, a single spaceborne sensor cannot deliver information in both, high spatial and temporal detail. The SCATSAR-SWI ...

objective(s): epigenetic regulation of gene expression can be carried out through chromatin remodeling enzymes such as swi/snf. brg1 also known as smarca4 is a catalytic subunit of swi/snf, which is necessary for mmps expression. matrix metalloproteinases (mmps) are known as important player enzymes during tumor progression and metastasis. aberrant epigenetic modification of chromatin should be...

Introduction: Brain iron content is a potential biomarker for several neurological diseases. Due to its high sensitivity to changes in iron content, susceptibility weighted imaging (SWI) [1] [2] has been gaining popularity in the imaging of neurodegenerative diseases, such as multiple sclerosis [3], Parkinson disease [4], or Huntington's disease. However, the metrics obtained with gradient echo...

BACKGROUND AND PURPOSE Impaired cortical venous outflow and abnormal deep venous collaterals are common in Sturge-Weber syndrome (SWS), but their relation to brain metabolism and function is poorly understood. In this study, advanced MR imaging techniques, such as susceptibility-weighted imaging (SWI) and diffusion tensor imaging (DTI), were applied in conjunction with positron-emission tomogra...

The Prolog programmer’s needs have always been the focus for guiding the development of the SWI-Prolog system. This article accompanies an invited talk about how the SWI-Prolog environment helps the Prolog programmer solve common problems. It describes the central parts of the graphical development environment as well as the command line tools which we see as vital to the success of the system....

The RNA polymerase II holoenzyme contains RNA polymerase II, a subset of general transcription factors and SRB regulatory proteins. We report here that SWI and SNF gene products, previously identified as global gene regulators whose functions include remodeling chromatin, are also integral components of the yeast RNA polymerase II holoenzyme. The SWI/SNF proteins are components of the SRB compl...

The Prolog programmer’s needs have always been the focus for guiding the development of the SWI-Prolog system. This article accompanies an invited talk about how the SWI-Prolog environment helps the Prolog programmer solve common problems. It describes the central parts of the graphical development environment as well as the command line tools which we see as vital to the success of the system....

In this paper a design of a computer simulator of susceptibility weighted imaging (SWI) protocol is presented. The ultimate application of the proposed system is to provide a framework for quantitative validation of SWI image processing algorithms. SWI is based on field non-uniformity caused by local susceptibility distribution and thus resulting in both measured signal phase shift and faster d...