Purpose: To assess the association betweenpreoperative serum total testosterone (tT), 17b-estradiol (E2), sex hormone–binding globulin (SHBG), and tT–E2 ratio values with high-risk prostate cancer (as defined by the National Comprehensive Cancer Network practice guidelines) at radical prostatectomy. Experimental Design: Serum E2, tT, and SHBG were dosed the day before surgery (7:00–11:00 am) in...

BACKGROUND Real-world prescription pathways leading to triple therapy (TT) (inhaled corticosteroid [ICS] plus long-acting β2-agonist bronchodilator [LABA] plus long-acting muscarinic antagonist) differ from Global initiative for chronic Obstructive Lung Disease [GOLD] and National Institute for Health and Care Excellence treatment recommendations. This study sets out to identify COPD patients w...

INTRODUCTION Loss of penile length is a recognized and common consequence of Peyronie's disease (PD). Traction therapy (TT+) has been reported to decrease post-op length loss as well as increase stretched penile length (SPL) prior to surgery. AIM The aim of this study was to study patient outcomes with penile length change and patient satisfaction after surgery following tunica albuginea plic...

AIM To investigate the eligibility of patients with acute myocardial infarction (AMI) for thrombolytic therapy (TT) and evaluate the results of treatment. METHODS Retrospective analysis included 366 patients with AMI, mean age 66+/-11 years, treated in 1999. We analyzed age, gender, previous infarction, previous TT, present TT with streptokinase and its effects on the course and outcome, pain...

Methods Forty nine subjects undergoing clinically indicated right and left heart cardiac catheterization were prospectively recruited to undergo MRI in a 1.5T scanner. First pass perfusion using steady state free precession saturation recovery sequence was performed with gadolinium infusion at 0.01 mmol/kg. Global TT was defined as the time between the peaks of time intensity curves between the...

Time-triggered (TT) Ethernet is a novel communication system that integrates real-time and non-real-time traffic into a single communication architecture. A TT Ethernet system consists od a set of nodes interconnected by a specific switch called TT Ethernet switch. A node consist of a TT Ethernet communication controller that executes the TT Ethernet protocol and a host computer that executes t...

PURPOSE To assess the association between preoperative serum total testosterone (tT), 17β-estradiol (E(2)), sex hormone-binding globulin (SHBG), and tT-E(2) ratio values with high-risk prostate cancer (as defined by the National Comprehensive Cancer Network practice guidelines) at radical prostatectomy. EXPERIMENTAL DESIGN Serum E(2), tT, and SHBG were dosed the day before surgery (7:00-11:00...

Extracytoplasmic function (ECF) σ factors, the largest group of alternative σ factors, play important roles in response to environmental stresses. Tt-RpoE1 is annotated as an ECF σ factor in Thermoanaerobacter tengcongensis. In this study, we revealed that the Tt-tolB gene located downstream of the Tt-rpoE1 gene encoded the cognate anti-σ factor, which could inhibit the transcription activity o...