نتایج جستجو برای: سیگنال pcg
تعداد نتایج: 7011 فیلتر نتایج به سال:
Abstract Mineau (1998) has developed a state-transition based extension to Sowa’s Conceptual Structures Theory (1984) called processes, which permits the dynamic update of a knowledge base of conceptual graphs. This formalism is a generalisation of Delugach’s (1991) demons, and Sowa’s actors or dataflow graphs, although the process mechanism also utilises the latter in practice. This paper pres...
Genes belonging to the Polycomb-group (PcG) are epigenetic gene silencers with a vital role in the maintenance of cell identity. They contribute to regulation of various processes in both embryos and adults, including the cell cycle and lymphopoiesis. A growing body of work has linked human PcG genes to various hematological and epithelial cancers, identifying novel mechanisms of malignant tran...
Polycomb-group (PcG) proteins form large multimeric protein complexes that are involved in maintaining the transcriptionally repressive state of genes. Previously, we reported that RING1 interacts with vertebrate Polycomb (Pc) homologs and is associated with or is part of a human PcG complex. However, very little is known about the role of RING1 as a component of the PcG complex. Here we undert...
BACKGROUND Primary congenital glaucoma (PCG), occurs due to the developmental defects in the trabecular meshwork and anterior chamber angle in children. PCG exhibits genetic heterogeneity and the CYP1B1 gene has been widely implicated worldwide. Despite the diverse mutation spectra, the clinical implications of these mutations are yet unclear. The present study attempted to delineate the clinic...
Let T be an edge weighted tree, let dT (u, v) be the sum of the weights of the edges on the path from u to v in T , and let dmin and dmax be two non-negative real numbers such that dmin ≤ dmax. Then a pairwise compatibility graph of T for dmin and dmax is a graph G = (V, E), where each vertex u ∈ V corresponds to a leaf u of T and there is an edge (u, v) ∈ E if and only if dmin ≤ dT (u, v) ≤ dm...
PURPOSE To investigate variations in sex ratio among Iranian primary congenital glaucoma (PCG) patients with and without mutations in the CYP1B1 gene and to evaluate possible clinical variations associated with sex in these two groups. METHODS Phenotypical data on 104 unrelated Iranian PCG patients who had previously been screened for CYP1B1 mutations were analyzed. Emphasis was placed on ana...
Plasma cell infiltrates in the thyroid are rare. They may represent several processes, such as localized plasmacytoma, multiple myeloma, or plasma cell granuloma (PCG). It may be difficult to distinguish these disorders on the basis of morphologic features in sections stained with hematoxylin-eosin. All may be composed of mature plasma cells, without admixed macrophages or lymphocytes, that inf...
BACKGROUND Polycomb-group (PcG) and trithorax-group (trxG) proteins regulate histone methylation to establish repressive and active chromatin configurations at target loci, respectively. These chromatin configurations are passed on from mother to daughter cells, thereby causing heritable changes in gene expression. The activities of PcG and trxG proteins are regulated by a special class of prot...
To comply with recent international trends and initiatives, and in order to help achieve sustainable development, Korea has established a greenhouse gas (GHG) emission reduction target of 37% (851 million tons) of the business as usual (BAU) rate by 2030. Regarding environmentally-oriented standards such as the IGCC (International Green Construction Code), there are also rising demands for the ...
Heart murmurs have been found to be a life threatening condition for the newborns who are born with cardiac abnormalities. The first sign of pathological changes of heart valves appear in phonocardiogram (PCG) which contains very useful information about cardiovascular system. It is a challenging venture to distinguish pathological murmurs from innocent ones. In this paper, we have developed a ...
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