The synaptonemal complex (SC) is a widely conserved structure that mediates the intimate alignment of homologous chromosomes during meiotic prophase and is required for proper homolog segregation at meiosis I. However, fundamental details of SC architecture and assembly remain poorly understood. The coiled-coil protein, Zip1, is the only component whose arrangement within the mature SC of buddi...

The proposed paper gives a brief survey of situational control (SC) of complex systems development, also a brief survey of applications that were realized in the past period (SC of robotic technological complexes, SC of electric network, SC in metallurgy, SC in biomedicine, situational modeling, situational classification in projecting, etc.) The paper also deals with problems of decision – mak...

Consider a multi-channel supply chain (hereafter SC) system, producing and distributing two substitutable products. Within this framework, we study the SC efficiency by comparing several decentralized SC configurations with a centralized one. Our result show that it is often possible to achieve 93.5% or more of the total profit of a centralized SC in a decentralized configuration, which suggest...

social capital (sc) is important as much as physical capital and theorists discussed its functions in enhancement of countries. successfulness in international fields is far behind reach without due attention to capacity of countries. these capacities are known as competitiveness capacity (cc) in political literature. twelve indexes have been recognized for the cc which covers different dimensi...

The concept of in-air output ratio (Sc) was introduced to characterize how the incident photon fluence per monitor unit (or unit time for a Co-60 unit) varies with collimator settings. However, there has been much confusion regarding the measurement technique to be used that has prevented the accurate and consistent determination of Sc. The main thrust of the report is to devise a theoretical a...

Obatoclax is a small molecule which targets the Bcl-2 family, and is to treat leukemia, lymphoma and lung carcinoma. Previously, an obatoclax analogue, SC-2001, was found to disrupt the protein-protein interactions of the Bcl-2 family and also repress Bcl-XL and Mcl-1 expression via STAT3 inactivation. Here, we report a novel mechanism of autophagy induction by SC-2001 in liver cancer cells. Th...

Mg/Sc and Sc/Mg bilayers were studied to investigate their interfaces. Time-of-flight secondary ion mass spectroscopy grazing incidence x-ray reflectivity are combined determine the realistic structure of bilayer stack: thickness, refractive index, roughness layers interlayers respectively. In addition, soft measurements provide sensitive information about chemical environment scandium, when in...

Macrodiversity system including macrodiversity SC receiver and two microdiversity SC receivers is considered in this paper. Received signal experiences, simultaneously, both, long term fading and short term fading. Microdiversity SC receivers reduce Rayleigh fading effects on system performance and macrodiversity SC receivers mitigate Gamma shadowing effects on system performance. Closed form e...

Macrodiversity system with macrodiversity selection combining (SC) receiver and two microdiversity SC receivers is considered. Received signal is affected simultaneously to Gamma long term fading and Rician short term fading resulting in system performance degradation. Macrodiversity SC receiver reduces Gamma shadowing effects and microdiversity SC receivers reduce multipath fading effects on b...