نتایج جستجو برای: سیستم ایمنی مصنوعی ais

تعداد نتایج: 96987  

Journal: :Human molecular genetics 2014
Jillian G Buchan David M Alvarado Gabe E Haller Carlos Cruchaga Matthew B Harms Tianxiao Zhang Marcia C Willing Dorothy K Grange Alan C Braverman Nancy H Miller Jose A Morcuende Nelson Leung-Sang Tang Tsz-Ping Lam Bobby Kin-Wah Ng Jack Chun-Yiu Cheng Matthew B Dobbs Christina A Gurnett

Adolescent idiopathic scoliosis (AIS) causes spinal deformity in 3% of children. Despite a strong genetic basis, few genes have been associated with AIS and the pathogenesis remains poorly understood. In a genome-wide rare variant burden analysis using exome sequence data, we identified fibrillin-1 (FBN1) as the most significantly associated gene with AIS. Based on these results, FBN1 and a rel...

Journal: :Scientific reports 2016
Zhi-jian Sun Hong-mei Jia Gui-xing Qiu Chao Zhou Shigong Guo Jian-guo Zhang Jian-xiong Shen Yu Zhao Zhong-mei Zou

Adolescent idiopathic scoliosis (AIS) is a complex spine deformity, affecting approximately 1-3% adolescents. Earlier diagnosis could increase the likelihood of successful conservative treatment and hence reduce the need for surgical intervention. We conducted a serum metabonomic study to explore the potential biomarkers of AIS for early diagnosis. Serum metabolic profiles were firstly explored...

Journal: :Annals of neurology 2008
Timothy J Bernard Neil A Goldenberg Jennifer Armstrong-Wells Catherine Amlie-Lefond Heather J Fullerton

Traditional risk factors associated with adult arterial ischemic stroke (AIS; ie, hypertension, hyperlipidemia, diabetes, smoking, and atherosclerosis) are relatively rare in children. Childhood AIS is instead associated with a variety of conditions including cerebral arteriopathies, congenital heart disease, infection, head and neck trauma, sickle cell anemia, and prothrombotic abnormalities. ...

Journal: :The Kobe journal of medical sciences 2014
Fumi Kawakami Shuho Semba Hiroe Itami Noriko Oka Tamotsu Sudo Yasuhiko Ebina Chiho Ohbayashi Yoshiki Mikami Hiroshi Yokozaki Tomoo Itoh

To determine the etiology of combined high-grade squamous intraepithelial lesion (HSIL) and adenocarcinoma in situ (AIS) of the uterine cervix, we examined human papillomavirus (HPV) subtypes, methylation status of the HPV-16 L1 gene, and immunohistochemical staining pattern of Krt7 in 8 cases of combined HSIL and AIS. Overall, 6 (75%) of 8 patients with combined HSIL and AIS were infected by t...

2015
Hirotaka Iwaki Masaru Kuriyama Shuichiro Neshige Shinichi Takeshima Takahiro Himeno Kazuhiro Takamatsu Yutaka Shimoe Hiromitsu Kobayashi Masahiro Nomoto Akio Tanaka

We report 10 cases with arterial ischemic stroke (AIS) with nephrotic syndrome (NS), and clarified its incidence and clinical characteristics. The patients having albumin less than 3.0 g/dl and serum cholesterol greater than 250 mg/dl at the same time were retrospectively screened from 11,161 cases of stroke. Furthermore, the patients of AIS showing heavy proteinuria were selected. The 10 cases...

Journal: :Stroke 2013
Jason D Hinman Matthew N Rasband S Thomas Carmichael

BACKGROUND AND PURPOSE Recovery from stroke requires neuroplasticity within surviving adjacent cortex. The axon initial segment (AIS) is the site of action potential initiation and a focal point for tuning of neuronal excitability. Remodeling of the AIS may be important to neuroplasticity after stroke. METHODS Focal cortical stroke in forelimb motor cortex was induced by photothrombosis and c...

آراسته, مهشید, دستباز, عقیل, سلطان دلال, محمدمهدی, صلصالی, مریم, محمدی, حمیدرضا, نمدی, کبری, نوروز بابایی, حمیده, واحدی, سعید, کفاشی, تاج الملوک,

زمینه و هدف : افزودنی‌های مواد غذایی یک واژه کلی برای ترکیباتی است که به منظور دوام یا بهتر نمودن ظاهر غذا، ترکیب، طعم و ارزش غذایی به مواد غذایی اضافه می‌شود. رنگ‌ها نیز جزو این دسته از مواد بوده که برای افزایش جذابیت مواد غذایی به آنها افزوده می‌شوند. رنگ‌ها می‌توانند عوارضی شبیه آسم، کهیر هایپراکتیویتی در کودکان، تضعیف سیستم ایمنی، واکنش‌های آنافیلاکتیک ویا حتی اثرات سرطان‌زایی داشته باشند. ...

2013
Janusz Piotr Tomasz Kotwicki Miroslaw Andrusiewicz Malgorzata Kotwicka

Background It has been suggested that XbaI single nucleotide polymorphism (SNP) (A/G rs934099) in estrogen receptor 1 (ESR1) may be associated with curve severity in Japanese AIS patients [1] and with both curve severity and predisposition for AIS in Chinese patients [2]. However, replication studies have not confirmed these findings [3]. The role of the XbaI ESR1 polymorphism rs9340799 in AIS ...

2015
Florina Moldovan Amani Hassan Charlotte Zaouter Soraya Barchi Patrick Edery Pierre Drapeau Stefan Parent Shunmoogum A Patten

Introduction Many chromosomic locations have been linked with the AIS, however, no causative genes have been clearly identified. We recently identified two regions (3q12.1 and 5q13.3) containing possibly causative gene(S) of AIS (Edery et al. 2011). Our recent work identified diseasecausing variants in a gene (that we called PFK2) in French AIS families (Patten et al. submitted 2014). We sought...

2012
Yanfang Niu Harvinder Kalsi

In view of current IT integration development of SOA, this paper examines AIS design based on SOA, including information sources collection, accounting business process integration and real-time financial reports. The main objective of this exploratory paper is to facilitate AIS research combing the Web Service, which is often ignored in accounting and computer research. It provides a conceptua...

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