Early detection of cognitive impairment can prevent or delay the progress of cognitive dysfunction. In the field of neurology, the Clock Drawing Test (CDT) is one of the most popular instruments for detecting cognitive impairment in the elderly. In this paper, we present our preliminary study in developing the ClockReader System, a computerized sketch-based screening tool, based on the human ce...

Oxaliplatin-induced peripheral neurotoxicity (OPN) is commonly associated with peripheral hypersensitivity to cold sensations (CS) but the mechanism is unknown. We hypothesized that the transient receptor potential melastatin 8 (TRPM8), a putative cold and menthol receptor, contributes to oxaliplatin cold hypersensitivity. To determine whether the TRPM8 is involved in acute OPN, varying concent...

Objectives. To study the utility of the Mini-Cog test for detection of patients with cognitive impairment (CI) in primary care (PC). Methods. We pooled data from two phase III studies conducted in Spain. Patients with complaints or suspicion of CI were consecutively recruited by PC physicians. The cognitive diagnosis was performed by an expert neurologist, after formal neuropsychological evalua...

BACKGROUND This study examined the use of the Folstein Mini Mental Status Exam (MMSE) and the Clock Drawing Test (CDT) in predicting retrospective reports of driving problems among the elderly. The utility of existing scoring systems for the CDT was also examined. METHODS Archival chart records of 325 patients of a geriatric outpatient clinic were reviewed, of which 162 had CDT results (inclu...

methods campylobacter jejuni atcc 33291 and seven isolates donated from instituto de biotecnologia were used in this study. the presence of cdt genes in c. jejuni strains was determined by pcr. to evaluate the effect of cdt, hela cells were treated with bacterial lysate, and the damage and morphological changes were analyzed by microscopy, immunofluorescence staining, and flow cytometry. to eva...

Post-mastectomy chronic lymphedema as a complication of breast cancer treatment is primarily managed with Complete Decongestive Therapy (CDT). We examined various factors for correlating with results of Phase I CDT treatment in controlling the upper extremity lymphedema. Study population consisted of patients with lymphedema referred to the Lymphedema Clinic of the Iranian Breast Cancer Researc...

BACKGROUND Lymphedema treatment is difficult and there is no consensus on the best treatment. This study evaluated the effect of combined decongestive therapy (CDT) and pneumatic compression pump on lymphedema indicators in patients with breast cancer related lymphedema (BCRL). METHODS Twenty one women with BCRL were enrolled. The volume difference of upper limbs, the circumference at 9 areas...

A genetic locus for a cytolethal distending toxin (CDT) was identified in a polymorphic region of the chromosome of Actinobacillus actinomycetemcomitans, a predominant oral pathogen. The locus was comprised of three open reading frames (ORFs) that had significant amino acid sequence similarity and more than 90% sequence identity to the cdtABC genes of some pathogenic Escherichia coli strains an...

Operation of closed drift thruster (CDT) relies mainly on neutral gas, whose trajectory and distribution in the flow field have a significant influence performance. Neutral dynamics (NFD), also known as gas thruster, has received increased attention from researchers over past century, drawing to its CDT. This article will therefore review most recent research NFD At outset review, we provide qu...