BACKGROUND AND OBJECTIVES In spite of the high complete remission rate that chemotherapy achieves in acute myeloid leukemia with AML1-ETO gene rearrangement, relapse is a major cause of treatment failure in this condition. We aimed to determine a predictor of relapse with the real-time quantitative reverse transcription polymerase chain reaction (RQ-PCR) of AML1-ETO chimeric mRNA. DESIGN AND ...

OBJECTIVE Consumption of energy drinks is increasing amongst athletes and the general public. By virtue of their bioactive ingredients (including caffeine, taurine, glucuronolactone, and B-group vitamins) and paucity of calories, sugar-free "diet" versions of these drinks could be a useful aid for weight maintenance. Yet little is known about the acute influence of these drinks, and specificall...

This paper considers the matching problem with regional quotas, in particular, regional minimum quotas. Although such quotas are relevant in many real-world settings, there is a lack of strategy-proof mechanisms that consider regional minimum quotas. We first show that without any restrictions on the region structure, finding a feasible matching that satisfies all quotas is NP-complete. Then, a...

OBJECTIVE At present, there are a limited number of facilities in Turkey that can provide reliable real-time quantitative(RQ)-PCR BCR-ABL results. The present study aimed to test a cost-effective, in-house method of BCR-ABL quantification,including verification of the method by RQ-PCR validation tests. MATERIAL AND METHODS BCR-ABL and ABL target sequences were cloned into pJET1.2 vectors, fro...

Graphene oxide (GO) has proven to be a satisfactory DNA-sensor platform for applications in enzyme-free signal amplification, fluorescence-based amplification, and nanoparticle-based platforms because of its excellent electrical, thermal, and optical properties. In this study, we designed a novel platform for the fluorescence detection of biomolecules, using a fluorescent dye-labeled primer and...

PURPOSE To examine postural stability in glaucoma patients and subjects with no ocular disease. METHODS Twenty-four glaucoma (G) and 24 control (C) subjects participated (mean age [SD] G: 65.9 [5.5] years; C: 68.3 [5.2] years). Postural stability was measured using a force-balance platform under four conditions: eyes open/closed standing on a firm surface and eyes open/closed on a foam surfac...

We measured the oxygen consumption (QO2) of lung slices from rats and rabbits and the respiratory quotient (RQ) of lung slices from fed and fasted rats. The QO2 of lung slices is lowered within 24 h after the onset of food deprivation; this decrease in QO2 lasts during at least 2 additional days of fasting and is not eliminated by addition of glucose to the reaction medium. In fed rats the RQ o...

Wear tests were performed with polytetrafluoroethylene (PTFE) + Al2O3 nanocomposites on various manufactured surfaces to determine whether or not the wear resistance of these nanocomposites is a strong function of surface preparation. Four different surface finishes of grade 304 stainless steel counterfaces were used: electropolished (Rq = 88 nm), lapped (Rq = 161 nm), wet-sanded (Rq = 390 nm),...