The purpose of the present in vitro study was to compare the cytotoxic effect of two commercially available brands of mineral trioxide cement (ProRoot MTA and MTA Angelus), modified zinc oxide-eugenol cement (SuperEBA) and resin-modified glass ionomer cement (Vitrebond) using rat pulp cells (RPC-C2A) and human lung fibroblasts (MRC-5). The cells were cultured in typical culture conditions and e...

The purpose of this study was to determine if the adaptation of mineral trioxide aggregate (MTA) would differ when placed into simulated root canals of varying length when using two different placement and condensation methods. Hand condensation was compared to ultrasonic condensation. Eighty polyethylene tubes were divided into four groups of 20 tubes each. The tubes in the four groups were pr...

OBJECTIVE The aim of this in vitro study was to evaluate antimicrobial activities of three different pulp capping materials; Biodentine, mineral trioxide aggregate (MTA) Angelus, and Dycal against Enterococcus faecalis and their durability with time. MATERIALS AND METHODS Direct contact test was used for the assessment. Three sets of sealers were mixed and placed on microtiter plate wells: On...

Medial temporal lobe atrophy (MTA) is a recognized marker of Alzheimer's disease (AD), however, it can be prominent in frontotemporal lobar degeneration (FTLD). There is an increasing awareness that posterior atrophy (PA) is important in AD and may aid the differentiation of AD from FTLD. Visual rating scales are a convenient way of assessing atrophy in a clinical setting. In this study, 2 visu...

The purpose of the present study was to compare the cytotoxicity of mineral trioxide aggregate (MTA) to other commonly used retrofilling materials, Super-EBA and amalgam. This was accomplished using a cell viability assay for mitochondrial dehydrogenase activity in human periodontal ligament fibroblasts after 24-hr exposure to extracts of varying concentrations of the test materials, in both fr...

This study evaluated apical periodontal healing after root-end sealing using 4-META/MMA-TBB resin (SB), and root-end filling using reinforced zinc oxide eugenol cement (EBA) or mineral trioxide aggregate (MTA) when root canal infection persisted. Apical periodontitis was induced in mandibular premolars of beagles by contaminating the root canals with dental plaque. After 1 month, in the SB grou...

Material kedokteran gigi dikembangkan tidak hanya memiliki kemampuan antimikroba yang berguna untuk mencegah infeksi namun juga bersifat bioactive menginduksi terjadinya regenerasi sel serta membantu proses pembentukan tulang. Beberapa penelitian menunjukkan kesamaan komposisi MTA dan semen portland. Aceh kekayaan mineral alam melimpah memproduksi portland berstandar internasional. Penelitian i...

AIM: The present study assessed the effect of mineral trioxide aggregate (MTA) and photobiomodulation (PBM) on pulp capping exposed dogs’ teeth. METHODS: Forty-eight teeth in three mongrel dogs were randomly divided into two major groups; Group I where MTA was used as a agent II which both MTA+PBM used. groups equally subdivided according to observation period following completion Subgroup (A) ...

AIMS AND BACKGROUND Ezrin is a membrane-cytoskeleton linker protein involved in regulation of the growth and metastatic behavior of cancer cells. Metastatic tumor antigen (MTA) is a potential metastasis-associated protein. The objective of this study was to evaluate the expression of ezrin and MTA and their correlation with clinicopathological features in osteosarcomas of the jaw. METHODS We ...

BACKGROUND Pemetrexed (Alimta) is a new-generation multitargeted antifolate that inhibits several key enzymes in the de novo pathways of pyrimidine and purine biosynthesis, including thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT). Alimta has demonstrated antitumor activity in a broad array of human malignancies, e.g. breast, no...