نتایج جستجو برای: سطح پرتوانی naive

تعداد نتایج: 181677  

Journal: :Journal of immunology 2006
Yoshiko Watanabe Takashi Nakayama Daisuke Nagakubo Kunio Hieshima Zhe Jin Fuminori Katou Kenji Hashimoto Osamu Yoshie

The nervous systems affect immune functions by releasing neurohormones and neurotransmitters. A neurotransmitter dopamine signals via five different seven-transmembrane G protein-coupled receptors termed D1 to D5. The secondary lymphoid tissues are highly innervated by sympathetic nerve fibers that store dopamine at high contents. Lymphocytes also produce dopamine. In this study, we examined ex...

Journal: :Journal of immunology 2002
Katsuaki Sato Hiroshi Kawasaki Chikao Morimoto Naohide Yamashima Takami Matsuyama

Human memory CD4(+) T cells respond better to inflammatory CCLs/CC chemokines, CCL3 and CCL5, than naive CD4(+) T cells. We analyzed the regulatory mechanism underlying this difference. Memory and naive CD4(+) T cells expressed similarly high levels of CCR1; however, CCR5 was only expressed in memory CD4(+) T cells at low levels. Experiments using mAbs to block chemokine receptors revealed that...

Journal: :Journal of immunology 2000
E F Wagner N Hanna L D Fast N Kouttab P R Shank A Vazquez S Sharma

Recent studies have defined several phenotypic and molecular changes associated with the maturation of naive human B cells within the milieu of germinal centers. Although naive B cells serve as natural precursors to germinal center (GC)/memory (M) subpopulations, little is known about the physiological requirements for the survival of the naive B cell pool in the absence of cell-cell contact or...

2015
Peter Burton

We study an invariant of dynamical systems called naive entropy, which is defined for both measurable and topological actions of any countable group. We focus on nonamenable groups, in which case the invariant is two-valued, with every system having naive entropy either zero or infinity. Bowen has conjectured that when the acting group is sofic, zero naive entropy implies sofic entropy at most ...

Journal: :International immunology 2016
Daisuke Kamimura Yasunobu Arima Mineko Tsuruoka Jing-Jing Jiang Hidenori Bando Jie Meng Lavannya Sabharwal Andrea Stofkova Naoki Nishikawa Kotaro Higuchi Hideki Ogura Toru Atsumi Masaaki Murakami

KDEL receptor 1 (KDELR1) regulates integrated stress responses (ISR) to promote naive T-cell survival in vivo. In a mouse line having nonfunctional KDELR1, T-Red (naive T-cell reduced) mice, polyclonal naive T cells show excessive ISR and eventually undergo apoptosis. However, breeding T-Red mice with TCR-transgenic mice bearing relatively high TCR affinity rescued the T-Red phenotype, implying...

Journal: :Journal of immunology 2000
T Kato H Nariuchi

In this study, we examined in vitro the role of CTLA-4 costimulation in the polarization of naive CD4+ T cells toward the Th1 subset. When CTLA-4 costimulation was blocked by the inclusion of anti-CTLA-4 Fab in cultures during priming of naive CD4+ T cells with anti-CD3 in the presence of splenic adherent cells, they were polarized toward the Th2 subset. Conversely, the engagement of CTLA-4 wit...

Journal: :Neuropsychobiology 2008
Barbora Tislerova Martin Brunovsky Jiri Horacek Tomas Novak Miloslav Kopecek Pavel Mohr Vladimír Krajca

The aim of our study was to detect changes in the distribution of electrical brain activity in schizophrenic patients who were antipsychotic naive and those who received treatment with clozapine, olanzapine or risperidone. We included 41 subjects with schizophrenia (antipsychotic naive = 11; clozapine = 8; olanzapine = 10; risperidone = 12) and 20 healthy controls. Low-resolution brain electrom...

Journal: :Journal of Natural Language Processing 2013

Journal: :Journal of Physics: Conference Series 2019

Journal: :International Journal of Approximate Reasoning 2016

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