The purpose of this study was to evaluate the protein expression and gene amplification of epithelial growth factor receptor (EGFR) in intraepithelial neoplasias and squamous cell carcinoma of the cervix and to determine the value of EGFR in carcinogenesis, progression, and prognosis of cervical cancer. EGFR protein expression and gene amplification involved gene copy number in 75 cases of cerv...

OBJECTIVE To evaluate the usefulness of endocervical Gram stain smears in the diagnosis of Chlamydia trachomatis and Neisseria gonorrhoeae in a female population attending a STD clinic. METHODS 494 females attending a STD clinic and undergoing a speculum examination had endocervical specimens submitted for C trachomatis culture, direct fluorescent antibody testing (DFA), and N gonorrhoeae cul...

JAFMC Bangladesh. Vol 6, No 2 (December) 2010 18 JAFMC Bangladesh. Vol 6, No 2 (December) 2010 19 JAFMC Bangladesh. Vol 6, No 2 (December) 2010 20 Abstract Many a times the clinical and per operative diagnosis does not correlate with histopathological diagnosis. Aim of this study was to compare the clinical, peroperative and histopathological findings of different cases of fibroid uterus, dysfu...

Background The local tissue immune status may play a role in the progression of cervical cancer. The aim of our study is to examine the expression of HLA-I, CD8 and CD4 in various cervical diseases and investigate their association with cervical cancer. Methods We chose the tissues of cervical cancer, cervical intraepithelial neoplasia (CIN), chronic cervicitis and peri-cancer tissues, and th...

OBJECTIVES To study the treatment efficacy of tetracyclines and azithromycin in Mycoplasma genitalium positive patients attending an STD clinic. METHODS All M genitalium positive patients (34 men and 26 women) attending an STD clinic during a 6 month period were treated with antibiotics. All patients known to be partners of M genitalium positive patients and those who were M genitalium positi...

Utero cervix usually constitutes the majority of specimens received at histopathology section in department of pathology. A variety of rare but interesting lesions may occur in the cervix and create problems in diagnosis. Difficulties in distinction from well-differentiated adenocarcinoma can result in potentially major adverse consequences for the patient in the form of inappropriate therapy. ...

BACKGROUND To investigate the infection status and predominant genotype distribution of human papillomavirus (HPV) infection among Chinese patients with mucopurulent cervicitis (MPC) or cervical cancer (CC) in Hangzhou. METHODS Initially, 217 cases of healthy cervix controls (n=50), acute MPC (n=89), and CC (n=78) were included; samples were collected between January 1, 2010, and January 30, ...

Case Report A 42 year male patient presented with recurrent papule formation with little itching on his glans penis, which soon rupture and turn to an ulcer. Small ulcers coalesce to form larger ulcer (fig 1). This repeated bout of ulcer formation was going on for several months. He was circumscribed and no complaint with urination. In spite of various treatments received from various private p...