The distribution of neutrophilic microbial iron oxidation is mainly determined by local gradients of oxygen, light, nitrate and ferrous iron. In the anoxic top part of littoral freshwater lake sediment, nitrate-reducing and phototrophic Fe(II)-oxidizers compete for the same e(-) donor; reduced iron. It is not yet understood how these microbes co-exist in the sediment and what role they play in ...

Previously, iron core-gold shell nanoparticles (Fe@Au) have been shown to possess cancer-preferential cytotoxicity in oral and colorectal cancer (CRC) cells. However, CRC cell lines are less sensitive to Fe@Au treatment when compared with oral cancer cell lines. In this research, Fe@Au are found to decrease the cell viability of CRC cell lines, including Caco-2, HT-29, and SW480, through growth...

BACKGROUND Our objective was to determine if a biofortified variety of black bean can provide more bioavailable-iron (Fe) than a standard variety. Two lines of black beans (Phaseolus-vulgaris L.), a standard (DOR500; 59μg Fe/g) and biofortified (MIB465; 88μg Fe/g) were used. The DOR500 is a common commercial variety, and the MIB465 is a line developed for higher-Fe content. Given the high preva...

Dissolved iron (Fe) concentrations in the California coastal upwelling regime vary over two orders of magnitude (from ,0.05 to .5 nM), which leads to a wide range in Fe effects on phytoplankton growth. Fe-addition experiments are appropriate to use to assess the biological role of Fe in low-Fe areas, but other methods are needed in Fe-replete regions. We present experiments that use additions o...

All known nitrogenase cofactors are rich in both sulfur and iron and are presumed capable of binding and reducing N2. Nonetheless, synthetic examples of transition metal model complexes that bind N2 and also feature sulfur donor ligands remain scarce. We report herein an unusual series of low-valent diiron complexes featuring thiolate and dinitrogen ligands. A new binucleating ligand scaffold i...

Fe deficiency and Fe-deficiency anaemia are common in patients with inflammatory bowel disease (IBD). Traditional clinical markers of Fe status can be skewed in the presence of inflammation, meaning that a patient's Fe status can be misinterpreted. Additionally, Fe absorption is known to be down-regulated in patients with active IBD. However, whether this is the case for quiescent or mildly act...

Iron (Fe) is an essential plant micronutrient, and its deficiency limits plant growth and development on alkaline soils. Under Fe deficiency, plant responses include up-regulation of genes involved in Fe uptake from the soil. However, little is known about shoot responses to Fe deficiency. Using microarrays to probe gene expression in Kas-1 and Tsu-1 ecotypes of Arabidopsis thaliana, and compar...

Iron (Fe) is an essential micronutrient for virtually all living organisms; it is incorporated into numerous proteins as Fe-sulfur (S) clusters, heme, or free Fe, and it mediates many metabolic processes, including photosynthesis and cellular respiration. Due to the low solubility and high reactivity of Fe, living cells must tightly regulate Fe acquisition in response to changes in Fe availabil...

In plants, iron (Fe) is essential for mitochondrial electron transport, heme, and Fe-Sulphur (Fe-S) cluster synthesis; however, plant mitochondrial Fe transporters have not been identified. Here we show, identify and characterize the rice mitochondrial Fe transporter (MIT). Based on a transfer DNA library screen, we identified a rice line showing symptoms of Fe deficiency while accumulating hig...

The gas-phase reactions of Fe(CH2O) and Fe(CH2S) with a series of aliphatic alkanes were studied by Fourier transform ion cyclotron resonance (FTICR) mass spectrometry. Like bare Fe+, C-C insertion, particularly terminal C-C insertion, is predominant for the reactions of Fe(CH2O), while C-H insertion is preferred for Fe(CH2S). About 90% of the Fe(CH2O) reaction products are formed by C-C insert...