نتایج جستجو برای: روش ubc
تعداد نتایج: 370759 فیلتر نتایج به سال:
سابقه و هدف: یکی از بهترین راه های کنترل بیماری پوسیدگی طوقه و ریشه گوجه فرنگی ناشی از f. oxysporum f.sp. radicis-lycopersici استفاده از ارقام مقاوم می باشد. نشانگرهای مولکولی دارای همبستگی با ژن مقاومت، می توانند در برنامه های اصلاحی گوجه فرنگی مورد استفاده قرار گیرند. هدف از این پژوهش، شناسایی ارقام مقاوم (دارا بودن ژن frl) و حساس 27 رقم گیاه گوجه فرنگی با استفاده از نشانگر rapd بود. مو...
The retinoblastoma gene product has been implicated in the regulation of multiple cellular and developmental processes, including a well-defined role in the control of cell cycle progression. The Caenorhabditis elegans retinoblastoma protein homolog, LIN-35, is also a key regulator of cell cycle entry and, as shown by studies of synthetic multivulval genes, plays an important role in the determ...
Ubiquitin-conjugating enzyme E2s (UBCs), which catalyze the transfer of ubiquitin to substrate or E3 ligases, are key enzymes in ubiquitination modifications of target proteins. However, little is known about the knowledge of UBC gene family in rice. In this study, a total of 39 UBC encoding genes, which all contained an UBC domain with a cysteine active site, were identified in the rice genome...
Inhibitory synapses display a great diversity through varying combinations of presynaptic GABA and glycine release and postsynaptic expression of GABA and glycine receptor subtypes. We hypothesized that increased flexibility offered by this dual transmitter system might serve to tune the inhibitory phenotype to the properties of afferent excitatory synaptic inputs in individual cells. Vestibulo...
OBJECTIVE To describe the physical activity (PA) levels and counseling attitudes of Canadian undergraduate medical students. DESIGN Online or paper survey. SETTING The University of British Columbia (UBC). PARTICIPANTS Fourth-year medical students at UBC from 2007 to 2010. MAIN OUTCOME MEASURES Physical activity levels, relationship between exercise behaviour and attitudes toward counse...
OBJECTIVES Different types of '-omics' data are becoming available in the post-genome era; still a single -omics assessment provides limited insights to understand the biological mechanism of complex diseases. Genomics, epigenomics and transcriptomics data provide insight into the molecular dysregulation of neoplastic diseases, among them urothelial bladder cancer (UBC). Here, we propose a deta...
Recently, many studies explored the role of inflammation parameters in the prognosis of urinary cancers, but the results were not consistent. The modified Glasgow Prognostic Score (mGPS), a systemic inflammation marker, is a prognostic marker in various types of cancers. The aim of the present study was to investigate the usefulness of the preoperative mGPS as predictor of recurrence-free (RFS)...
Valid housekeeping genes (HKG) are a prerequisite for accurate gene quantification. We performed real-time reverse transcription-polymerase chain reaction to investigate the gene expression of five commonly used HKGs (beta-actin, glyceraldehyde-3-phosphate dehydrogenase [GAPDH], ubiquitin C [UBC], hypoxanthine phosphoribosyl-transferase [HPRT], and cyclophilin A [CYPa]) and antioxidant enzymes ...
BACKGROUND Hsf4 is closely related to the development of cataract. However, the molecular mechanisms remain unknown. This study aimed to explore the molecular mechanisms that how Hsf4 mutations influence development of lens and thus lead to cataract in mouse. METHODS The mRNA expression profile of mouse tissue samples from Hsf4-null and wile-type lenses was downloaded from Gene Expression Omn...
The ubiquitin conjugating enzyme E2 (UBC E2) mediates selective ubiquitination, acting with E1 and E3 enzymes to designate specific proteins for subsequent degradation. In the present study, we characterized the function of the mung bean VrUBC1 gene (Vigna radiata UBC 1). RNA gel-blot analysis showed that VrUBC1 mRNA expression was induced by either dehydration, high salinity or by the exogenou...
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