نتایج جستجو برای: روش mps

تعداد نتایج: 374469  

2016
Liza Grosman-Rimon William Parkinson Suneel Upadhye Hance Clarke Joel Katz John Flannery Philip Peng Dinesh Kumbhare

The aims of the present study were to compare levels of circulating inflammatory biomarkers and growth factors between patients with myofascial pain syndrome (MPS) and healthy control participants, and to assess the relationship among inflammatory markers and growth factors in the two groups.Biomarkers levels were assessed in patients (n = 37) with myofascial pain complaints recruited from the ...

2013
Jung-Joon Cha Jong-Youn Kim Eui-Young Choi Pil-Ki Min Minhee Cho Da-Lyung Lee Sung-Yu Hong Young-Won Yoon Byoung Kwon Lee Bum-Kee Hong Se-Joong Rim Hyuck Moon Kwon

BACKGROUND AND OBJECTIVES We investigated the effect of the additional use of abciximab during percutaneous coronary intervention (PCI) on the level of procoagulant microparticles (MPs) in patients with ST-segment elevation myocardial infarction (STEMI) who had undergone primary PCI. SUBJECTS AND METHODS In this study, we studied 86 patients with STEMI (72 men, age 58±13) who had undergone pr...

2017
Ainslie L K Derrick-Roberts Matilda R Jackson Carmen E Pyragius Sharon Byers

Mucopolysaccharidosis type I (MPS I) is the most common form of the MPS group of genetic diseases. MPS I results from a deficiency in the lysosomal enzyme α-l-iduronidase, leading to accumulation of undegraded heparan and dermatan sulphate glycosaminoglycan (GAG) chains in patient cells. MPS children suffer from multiple organ failure and die in their teens to early twenties. In particular, MPS...

Journal: :Blood 2015
Stéphane M Camus João A De Moraes Philippe Bonnin Paul Abbyad Sylvain Le Jeune François Lionnet Laurent Loufrani Linda Grimaud Jean-Christophe Lambry Dominique Charue Laurent Kiger Jean-Marie Renard Claire Larroque Hervé Le Clésiau Alain Tedgui Patrick Bruneval Christina Barja-Fidalgo Antigoni Alexandrou Pierre-Louis Tharaux Chantal M Boulanger Olivier P Blanc-Brude

Intravascular hemolysis describes the relocalization of heme and hemoglobin (Hb) from erythrocytes to plasma. We investigated the concept that erythrocyte membrane microparticles (MPs) concentrate cell-free heme in human hemolytic diseases, and that heme-laden MPs have a physiopathological impact. Up to one-third of cell-free heme in plasma from 47 patients with sickle cell disease (SCD) was se...

2017
Kevin D. Tipton

• The metabolic basis for changes in muscle mass is net muscle protein balance, i.e., the balance between muscle protein synthesis (MPS) and muscle protein breakdown (MPB). Changes in MPS are responsible for a much greater proportion of the change in net muscle protein balance than are changes in MPB. • Many factors influence the response of MPS to protein ingestion following resistance exercis...

2017
Yuchen Zhang Junjun Cheng Fang Chen Changyan Wu Junmeng Zhang Xuejun Ren Yu Pan Bin Nie Quan Li Yu Li

Microparticles (MPs) and miRNAs have been shown to play important roles in coronary artery disease (CAD) by monitoring endothelial dysfunction. The present study aims to investigate the diagnostic value of endothelial MPs (EMPs) and miRNAs (miR-92a or miR-23a) as biomarkers in distinguishing patients with acute myocardial infarction (AMI) from those with CAD. Plasma samples from 37 patients wit...

2015
Sounik Sarkar Anjan Kr Dasgupta

Microparticles (MPs) have great potentiality in material science- based applications. Their use in biology is however limited to clinics and has rarely been exploited in the pharmaceutical context. Unlike nanoparticles (NPs), they are amenable to routine detection by flow cytometry and confocal microscopy. Though MPs can constitute a wide variety of materials, including ceramics, glass, polymer...

Journal: :Journal of controlled release : official journal of the Controlled Release Society 2010
Hilliard L Kutscher Piyun Chao Manjeet Deshmukh Yashveer Singh Peidi Hu Laurie B Joseph David C Reimer Stanley Stein Debra L Laskin Patrick J Sinko

The relationship between microparticle (MP) size and lung targeting efficiency, intra-lung distribution and retention time was systematically studied after intravenous administration of rigid fluorescent polystyrene MPs of various sizes (2, 3, 6 and 10 microm) to Sprague Dawley rats. Total fluorescence was assessed and it was found that 2 microm and 3 microm MPs readily passed through the lung ...

2017
Allison L. Teunis Taissia G. Popova Virginia Espina Lance A. Liotta Serguei G. Popov

We recently reported that the open-mesh (0.7 μ) polyacrylamide microparticles (MPs) with internally-coupled Cibacron affinity dye demonstrate protective effect in mice challenged into footpads with high doses (200 LD50) of anthrax (Sterne) spores. A single injection of MPs before spore challenge reduces inflammatory response, delays onset of mortality and promotes survival. In this study, we sh...

2017
Chin-Chou Wang Chia-Cheng Tseng Huang-Chih Chang Kuo-Tung Huang Wen-Feng Fang Yu-Mu Chen Cheng-Ta Yang Chang-Chun Hsiao Meng-Chih Lin Chi-Kung Ho Hon-Kan Yip

We investigated whether circulating microparticles (MPs) could serve as prognostic biomarkers in non-small cell lung cancer (NSCLC) patients. We enrolled 25 control subjects and 136 NSCLC patients categorized into disease-progression (DP, n=42) and disease-control (DC, n=94) groups. Flow cytometric analysis showed that levels of four types of circulating microparticles (EDAc-MPs, EDAp-MPs, PDAc...

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