نتایج جستجو برای: روش mpn
تعداد نتایج: 371287 فیلتر نتایج به سال:
A rapid and precise assay for neuraminidase using 2-(3'-methoxyphenyl)-N-acetyl-alpha-neuraminic acid (MPN) is described. It is proposed that this substrate be used for the standardization of activity of neuraminidases from viral, bacterial, and mammalian sources. MPN is also used as a chromogenic substrate to localize influenza and parainfluenza virus foci in tissue culture. This technique per...
The JAK2(V617F) mutation does not elucidate the phenotypic variability observed in myeloproliferative neoplasm (MPN) families. A putative tumor suppressor gene, TET2, was recently implicated in MPN and myelodysplastic syndromes through the identification of acquired mutations affecting hematopoietic stem cells. The present study analyzed the TET2 gene in 61 MPN cases from 42 families. Fifteen d...
..........................................................................................1 CHAPTER I: INTRODUCTION....................................................................3 CHAPTER II: Steroidal Regulation of synaptic density in the magnocellular division of the medial preoptic nucleus (MPN mag) of the Syrian Hamster..............................19 Introduction.........................
Chronic myelomonocytic leukemia (CMML) is a myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) overlap syndrome characterized by peripheral blood monocytosis (absolute monocyte count/AMC ⩾ 1 × 10(9)/l, ⩾ 10% of the total white blood cell count) and an inherent risk for leukemic transformation. Monocytosis, however, is not pathognomic for CMML and can be associated with reactive and ...
The Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) are a group of clonal hematopoietic diseases characterized by bone marrow proliferation of one or more of the myeloid cell lineages with no marked alterations in cellular maturation. MPN classically comprise the clinically and pathologically related polycythemia vera (PV), essential thromobocythemia (ET), and primary myelof...
سابقه و هدف: واکنش زنجیره ای پلی مرآز (polymerase chain reaction pcr) از نظر سرعت، دقت و کارآیی نسبت به سایر روش های تشخیص اشریشیاکلی در آب، ارجحیت دارد. بروز نتایج مثبت کاذب از معایب این روش است و برای رفع این مشکل می-توان از واکنش زنجیره ای پلی مرآز معکوس (reverse transcriptase- polymerase chain reaction rt-pcr) استفاده نمود. در این تحقیق سعی گردیده تا علاوه بر تعیین کارآیی روش rt-pcr، میزان ...
Objective Primary myelofibrosis (PMF) is one of the Philadelphia negative myeloproliferative neoplasms (MPN). The main clinical features are obvious physical symptoms and symptomatic splenomegaly. It may be converse to leukemia and has a shortened life expectancy. Nowadays, the therapy for PMF is aimed at maintaining comfort and there is no curative treatment. PMF with myelodysplastic syndrome ...
OBJECTIVE LNK is an adapter protein negatively regulating the JAK/STAT cell signaling pathway. In this study, we observed the correlation between variation in LNK gene and the clinical type of myeloproliferative neoplasms (MPN). METHODS A total of 285 MPN cases were recruited, including essential thrombocythemia (ET) 154 cases, polycythemia vera (PV) 76 cases, primary myelofibrosis (PMF) 19 c...
One hundred and eighteen oyster samples collected from local markets and oyster farms in southern Thailand were examined for noroviruses (NoVs) and bacterial indicators of fecal contamination (fecal coliforms and Escherichia coli). Using a virus concentration procedure followed by RT-nested PCR, NoVs were detected in 38% of the samples. Oysters collected from oyster farms were found with NoVs a...
Ruxolitinib is a small-molecule inhibitor of the JAK kinases, which has been approved for the treatment of myelofibrosis, a rare myeloproliferative neoplasm (MPN), but clinical trials are also being conducted in inflammatory-driven solid tumors. Increased infection rates have been reported in ruxolitinib-treated patients, and natural killer (NK) cells are immune effector cells known to eliminat...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید