Using the isolation of Mycobacterium bovis as the reference standard, this study evaluated the sensitivity, specificity and kappa statistic of gross pathology (abattoir postmortem inspection), histopathology, and parallel or series combinations of the two for the diagnosis of tuberculosis in 430 elk and red deer. Two histopathology interpretations were evaluated: histopathology I, where the pre...

We have previously reported that intrauterine (i/u) administration of epidermal growth factor (EGF 500 ng) on day (d) 21 of pregnancy delayed 19.0 +/- 0.6 h the onset of labor. Progesterone (P) is secreted by ovarian corpora lutea (CL) throughout gestation in the rat. Prepartum CL regression due to increased uterine cyclooxygenase I and prostaglandin F(2alpha) results in P withdrawal followed b...

The halogen concentrations of a number of Martian meteorites vary significantly, with larger variations observed in I/Cl compared to Br/Cl. One striking feature is the high I/Cl ratios associated with those meteorites found in Antarctica. Removal of low temperature, superficial contamination does not significantly reduce the I/Cl ratio [1], indicating that processing in Antarctica is responsibl...

Pendrin (Slc26a4) localizes to type B and non-A, non-B intercalated cells in the distal convoluted tubule, the connecting tubule, and the cortical collecting duct (CCD), where it mediates apical Cl(-)/HCO(3)(-) exchange. The purpose of this study was to determine whether angiotensin II increases transepithelial net chloride transport, J(Cl), in mouse CCD through a pendrin-dependent mechanism. J...

The centrosymmetric dinuclear Cu(II) complex, [Cu(2)Cl(4)(C(24)H(21)N(5)O(4))(2)], was synthesized by the reaction of CuCl(2)·2H(2)O with the tripodal ligand 2,2'-[3-(1H-imid-azol-4-ylmeth-yl)-3-aza-pentane-1,5-di-yl]diphthalimide (L). Each of the Cu(II) ions is coordinated by two N atoms from the ligand, two bridging Cl atoms and one terminal Cl atom. The Cu(II) coordination can be best be des...

In the title salt, [ZnCl(C(6)H(7)N(3))(2)]Cl·2H(2)O, the pyridine-2-carboximidamide ligands chelate to the Zn(II) atom, which is also coordinated by a Cl atom. The Zn(II) atom shows a trigonal-bipyramidal coordination, with the pyridyl N atoms occupying the axial positions. The cation, anion and water mol-ecules are linked by N-H⋯Cl, N-H⋯O, O-H⋯Cl and O-H⋯O hydrogen bonds into a three-dimension...

The assignments structures of the four 1:1 pipemidic acid (pipH)–magnesium(II), calcium(II), zinc(II), and iron(III) complexes, [Mg(pip)(H2O)3(Cl)].6H2O, [Ca(pip)(H2O)3(Cl)].2H2O, [Zn(pip)(H2O)3(Cl)].4H2O, [Fe(pip)(H2O)2(Cl)2].6H2O, (where pip = deprotonated pipemidic), were synthesized through chemical reactions MgCl2.6H2O, CaCl2.2H2O, ZnCl2, FeCl3.6H2O metal salt chlorides with pipH chemother...

The Mu2e experiment at Fermilab will search for the neutrinoless μ−→e− conversion in field of an aluminum nucleus. data-taking plan assumes two running periods, Run I and II, separated by approximately two-year-long shutdown. This paper presents estimate expected sensitivity includes a detailed discussion background sources, uncertainties their prediction, analysis procedures, optimization expe...

Ischemic injury to the CNS results in loss of ionic homeostasis and the development of neuronal death. An increase in intracellular Ca2+ is well established, but there are few studies of changes in intracellular Cl- ([Cl-]i) after ischemia. We used an in vitro model of cerebral ischemia (oxygen-glucose deprivation) to examine changes in [Cl-]i and GABA(A) receptor-mediated responses in hippocam...