BACKGROUND The analysis of the Auditory Brainstem Response (ABR) is of fundamental importance to the investigation of the auditory system behaviour, though its interpretation has a subjective nature because of the manual process employed in its study and the clinical experience required for its analysis. When analysing the ABR, clinicians are often interested in the identification of ABR signal...

The T lymphocytes are the most important effector cells in immunotherapy of cancer. The conceptual objective for developing the tumor targeted superantigen (TTS) ABR-217620 (naptumomab estafenatox, 5T4Fab-SEA/E-120), now in phase 3 studies for advanced renal cell cancer, was to selectively coat tumor cells with cytotoxic T lymphocytes (CTL) target structures functionally similar to natural CTL ...

Abrin (ABR), a protein purified from the seeds of Abrus precatorius, induces apoptosis in various types of cancer cells. However, the detailed mechanism remains largely uncharacterized. By using a cDNA microarray platform, we determined that prohibitin (PHB), a tumor suppressor protein, is significantly upregulated in ABR-triggered apoptosis. ABR-induced upregulation of PHB is mediated by the s...

UNLABELLED The main issue regarding pediatric audiology diagnosis is determining procedures to configure reliable results which can be used to predict frequency-specific hearing thresholds. AIM To investigate the correlation between auditory steady-state response (ASSR) with other tests in children with sensorineural hearing loss. METHODS Prospective cross-sectional contemporary cohort stud...

The IEEE 802.14 working group is currently standardizing a new media access control (MAC) protocol for the emerging Hybrid Fiber Coax (HFC) networks. Crucial for the success of 802.14 will be its ability to support higher layer tra c services, namely, ATM Constant Bit Rate (CBR), Variable Bit Rate (VBR) and Available Bit Rate (ABR) tra c classes. In this study, we investigate the inter-operatio...

The Available Bit Rate (ABR) service in ATM networks uses end-to-end rate-based ow control to allow fair and eecient support of data applications over ATM networks. One of the architectural features in the ABR speciication 1] is the Virtual Source/Virtual Destination (VS/VD) option. This option allows a switch to divide an end-to-end ABR connection into separately controlled ABR segments by act...

The Available Bit Rate (ABR) service class of Asynchronous Transfer Mode networks uses a feedback control mechanism to adapt to varying link capacities. The Virtual Source/Virtual Destination (VS/VD) technique offers the possibility to segment the otherwise end-to-end ABR control loop into separate loops. The improved feedback delay and the control of ABR traffic inside closed segments provide ...