Research suggests that the size of the second language (L2) vowel inventory relative to the native (L1) inventory may affect the discrimination and acquisition of L2 vowels. Models of non-native and L2 vowel perception stipulate that naïve listeners' non-native and L2 perceptual patterns may be predicted by the relationship in vowel inventory size between the L1 and the L2. Specifically, having...

It is generally accepted that the presence of a second language (L2) has an impact on the neuronal substrates build up and used for language processing; the influence of the age of L2 exposure, however, is not established. We tested the hypothesis that the age of L2 acquisition has an effect on the cortical representation of a multilingual repertoire in 44 multilinguals with different age of ex...

Primary mediastinal (thymic) large B-cell lymphoma (PMBL) and diffuse large B-cell lymphoma (DLBCL) are tumors with distinct clinical and molecular characteristics that are difficult to distinguish by histopathologic and phenotypic analyses alone. Programmed cell death 1 ligand 2 (PD-L2) is a cell surface protein expressed by activated macrophages and dendritic cells that binds PD-1 on T cells ...

Let (X,d,μ) be a space of homogeneous type in the sense Coifman and Weiss, i.e. d is quasi metric on X μ positive measure satisfying doubling condition. Suppose that u v are two locally finite Borel measures (X,d,μ). Subject to pair weights side condition, we characterize boundedness Calderón–Zygmund operator T from L2(u) L2(v) terms A2 condition testing conditions. For every cube B⊂X, have fol...

This paper presents an investigation of hesitation strategies of intermediate learners of German as a second or foreign language (L2) when they take part in oral L2 tests. Previous studies of L2 hesitation strategies have focused on beginning and advanced L2 learners. They found that beginners tend to leave their hesitation pauses unfilled making their speech highly disfluent [17], while advanc...

Given two symplectic manifolds (M1, ω1), (M2, ω2) a Lagrangian correspondence is a Lagrangian submanifold L ⊂ (M1 ×M2,−ω1 ⊕ ω2). These are the central objects of the theory of holomorphic quilts as developed by Wehrheim and Woodward in [21]. Consider two Lagrangian correspondences Li ⊂ (Mi−1 ×Mi,−ωi−1 ⊕ ωi) for i = 1, 2. Let ∆ = {(x, y, z, t) ∈ M0 ×M1 ×M1 ×M2 | y = z} If L1 × L2 is transverse t...

SUMMARY Increasing evidence suggests that patients with L2-HGA have a predisposition to cerebral neoplasms. This may be related to the pathologic accumulation of L2-HG because high amounts of 2-HG have been found in brain neoplasms that have IDH1 mutations. Our experience, on the basis of 11 previously unreported cases of L2-HGA, 3 of which developed cerebral neoplasms during the course of the ...

Incoming papillomaviruses (PVs) depend on mitotic nuclear envelope breakdown to gain initial access to the nucleus for viral transcription and replication. In our previous work, we hypothesized that the minor capsid protein L2 of PVs tethers the incoming vDNA to mitotic chromosomes to direct them into the nascent nuclei. To re-evaluate how dynamic L2 recruitment to cellular chromosomes occurs s...