صلاخلا ــ ة : مت ةقرولا هذه يف ءاشنإ يف هدعاسملل مدقتم ماظن بناوج ذيفنتو ميمصت ضرع قتو و مي ءادأ حيحصت تارفش لأا ءاطخ ةليلق لا ةناتم ، ةينبم ىلع ءوفاكتلا رايتخا . موقي امه نيتيسيئر نيتفيظوب ةساردلا هذه يف مدقتملا ماظنلا : 1 ادأ باسحل ةيزاوتملا هاآاحملا ء تارفش حيحصت لأا ءاطخ ةليلق نمزب ةفاثكلا ادج ريصق ةنراقم ةمظنأب ةاآاحملا ةدوجوملا . 2 ةليلق ءاطخلأا حيحصت تارفشو فعضلا قطانم صحف نع ة...

De auteur bespreekt de relatie tussen cultuur en geestesziekte. Hij vraagt aandacht voor het probleem van universalisme versus particularisme waar antropologenmee geconfronteerd worden bij interdisciplinaire studies van psychiatrie. Het thema is misschien niet nieuw, maar de beschouwing komt voort uit de reacties van Zuid-Afrikaanse postgraduate studenten in de medische antropologie die deelnam...

In filamentous fungi, het loci (for heterokaryon incompatibility) are believed to regulate self/nonself-recognition during vegetative growth. As filamentous fungi grow, hyphal fusion occurs within an individual colony to form a network. Hyphal fusion can occur also between different individuals to form a heterokaryon, in which genetically distinct nuclei occupy a common cytoplasm. However, hete...

Background—Nearly universal cardiomyopathy in Duchenne muscular dystrophy (DMD) contributes to heart failure and death. Because DMD patients show myocardial fibrosis well before functional impairment, we postulated that earlier treatment using drugs with antifibrotic effect may be beneficial. Methods and Results—Three groups of 10 utrn / ;mdx, or “het” mice, deficient for dystrophin and haploin...

BACKGROUND Nearly universal cardiomyopathy in Duchenne muscular dystrophy (DMD) contributes to heart failure and death. Because DMD patients show myocardial fibrosis well before functional impairment, we postulated that earlier treatment using drugs with antifibrotic effect may be beneficial. METHODS AND RESULTS Three groups of 10 utrn(+/-);mdx, or "het" mice, deficient for dystrophin and hap...

Lake Malawi (Nyasa) is one of the few deep-water long-lived lakes that presently exist on earth. It lies in an uncompensated tectonic graben, controlled by differential vertical movements between the rift basin who subsides and the rift shoulders who are uplifted. Active tectonics is the major factor controlling the development and persistence ofthose deep lakes. For Lake Malawi (Nyasa), climat...

Gene flow within populations can occur by sexual and/or parasexual means. Analyses of experimental and in silico work are presented relevant to possible gene flow within the aspergilli. First, the discovery of mating-type (MAT) genes within certain species of Aspergillus is described. The implications for self-fertility, sexuality in supposedly asexual species and possible uses as phylogenetic ...

Chronic exposure to increased force environments (+G) has pronounced effects on the circadian and homeostatic regulation of body temperature (T(b)), ambulatory activity (Act), heart rate, feeding, and adiposity. By using the Brn 3.1 knockout mouse, which lacks vestibular hair cells, we recently described a major role of the vestibular system in mediating some of these adaptive responses. The pr...

Previous research has found that single heterosexual (Het) men have higher salivary testosterone (T) concentrations than partnered Het men. Here, we used both longitudinal and cross-sectional analyses to examine a more diverse population (n = 258) that included Het and non-heterosexual (Non-Het) women and men. Results showed that, for Het men (but not Het women) and Non-Het women (but not Non-H...

Hesperetin (HET) and naringenin (NGR) are flavanones found in citrus (oranges and grapefruit) and Aurantii Fructus Immaturus. The present study aims to investigate the inhibition potential of HET and NGR derivatives towards one of the most important phase II drug-metabolizing enzymes-uridine diphosphate (UDP)-glucuronosyltransferases (UGTs). We used trifluoperazine as a probe substrate to test ...