This study determined whether retinal degeneration during diabetes includes retinal neural cell apoptosis. Image analysis of retinal sections from streptozotocin (STZ) diabetic rats after 7.5 months of STZ diabetes identified 22% and 14% reductions in the thickness of the inner plexiform and inner nuclear layers, respectively (P < 0. 001). The number of surviving ganglion cells was also reduced...

Abstract Background Congenital heart disease is a leading cause of death in newborns and infants. The feasibility fetal cardiac surgery linked to extracorporeal circulation (ECC); therefore, cardioplegic solutions need be effective long-lasting. Methods Eighteen pregnant sheep were divided into an ECC-only group, St. Thomas’ Hospital solution (STH1) group (STH group), HTK preservation (Custodio...

20(S)-protopanaxadiol (PPD) is an active natural product which transformed from protopanaxadiol-type ginsenosides. The present study was conducted to evaluate the effects of PPD on myocardial ischemia/reperfusion (I/R) injury in a rat model. (20mg/kg) or positive-control drug Diltiazem (10mg/kg) administered daily for 7 days before left anterior descending I/R operation. After 2-hour reperfusio...

DIHS/DRESS is a severe adverse drug reaction characterized by persistent eruption associated with reactivation of herpesviruses. In acute phase the disease, purpura occasionally observed mainly in limbs. We recently demonstrated that area lower limbs correlates severity as assessed score. However, pathogenesis has not been examined. collected four patients DIHS and two erythema multiforme (EM)....

Introduction Hematopoiesis in mouse fetal liver starts at 10 days of gestation and begins to decline after 15 days of gestation [1]. During postnatal hematopoietic involution, hepatocyte volume rapidly increases, and four types of specialized junctions; i.e., adherens junctions, desmosomes, tight junctions and gap junctions, appear to be fully developed in liver cells [2]. Neonatal livers exami...

Abstract Cave burials are generally absent from historical periods in Europe. Consequently, the discovery of a post-medieval inhumation child buried with at least one bird head placed mouth Tunel Wielki (southern Poland) is an exceptional find. The aim this paper to discuss unique burial based on multiproxy analyses conducted human and avian remains, including genetic isotopic as well CT scans,...