The purpose of this study was to measure daily and seasonal evapotranspiration and daily crop coefficient of two common varieties of sunflower (Sirna and Euroflor) via drip-tape irrigation system. For this purpose, the sunflower water use was determined by daily monitoring of soil moisture at the depths of 10, 20, 30, 40 and 60 cm, and the crop evapotranspiration (ETC) was measured using volume...

Objective(s): siRNA may be a very promising tool for treatment of various diseases especially in cancer therapy due to high specificity. One of the main hurdles applications of siRNAs in vivo is optimization of the delivery strategy, especially the carrier systems. The aim of this study was to optimize siRNA delivery into suspended erythroleukemic cell line K562. Materials and Methods: We appli...

We present COBS — a model of a concurrent object-based computational system with handshakes as elementary actions of inter-process communication. Processes are considered to be partial views of the system. Their communication by asynchronous message passing and variable sharing is modeled by elementary processes on the same abstraction level. The same acts of computation and communication can b...

background: breast cancer is the most common diagnosed cancer among women in the world. snail1 plays a role in the development of the invasive phenotypes of cancer, neural cell differentiation, cell division and apoptosis in tumor cells. traces of snail1 in metastasis of breast cancer to bone are observed. the aim of this study was to investigate the effect of specific snail1 sirnas on the prol...

objective(s): sirna may be a very promising tool for treatment of various diseases especially in cancer therapy due to high specificity. one of the main hurdles applications of sirnas in vivo is optimization of the delivery strategy, especially the carrier systems. the aim of this study was to optimize sirna delivery into suspended erythroleukemic cell line k562. materials and methods: we appli...

The signal transduction of human programmed death ligand 1 (PD-L1), as an important checkpoint gene in the immune system, plays a key role internal function and survival cancer cells. In this paper, PD-L1-siRNA immunostimulatory IL-2 encoding plasmid DNA loaded by polyethylenimine (PEI) lipid nanoparticles (PEI-LNPs) were constructed. Its therapeutic effect on lung was evaluated, its physical p...

Gene therapy aims to silence an oncogene through RNA interference, or replace abnormal tumour suppressor via gene augmentation. In this study, we intended interference for PRKCA and augmentation PTEN with a view reduce growth in mouse model of breast cancer. Inorganic carbonate apatite nanoparticles (CA NPs) were utilized deliver the synthetic siRNA purified gene-carrying plasmid DNA both vitro...