STUDY OBJECTIVES Effects of chronic metabolic alkalosis and acidosis and their relation to central chemoregulation may differ between normocapnic and chronic hypercapnic patients with COPD. The relationship between responses of inspired ventilation (VI), mouth occlusion pressure (P(0.1)), and cerebral blood volume (CBV), to short-term changes in arterial PCO(2) was measured. PATIENTS AND METH...

We revisit and extend the Riccati theory, unifying continuous-time linear-quadratic optimal permanent sampled-data control problems in finite infinite time horizons. In a nutshell, we prove that following diagram commutes: \beginequation* \xymatrix@R=1.5cm@C=3.5cm (SD-DRE) & E^T,\Delta \ar[r]^T \to +\infty \ar[d]_\Vert \Delta \Vert 0 E^\infty,\Delta \ar[d]^\Vert (SD-ARE) (P-DRE) E^T \ar[r]_T E^...

BACKGROUND The regulation of contractility of the transplanted heart depends on circulating catecholamines resulting from cardiac denervation. Supersensitivity to circulating catecholamines may result from loss of presynaptic neuronal uptake or upregulation of postsynaptic beta-adrenergic receptors. METHODS AND RESULTS Dose-response curves using the beta-adrenergic receptor agonists isoprenal...

We study the viscous dissipation in pipe flows long channels with porous or semipermeable walls, taking into account both bulk of channel and pores. give simple closed-form expressions for terms axially varying flow rate $Q(x)$ pressure $p(x)$, generalizing well-known expression $\stackrel{\ifmmode \dot{}\else \.{}\fi{}}{W}=Q\phantom{\rule{0.16em}{0ex}}\mathrm{\ensuremath{\Delta}}p=R{Q}^{2}$ ca...

With lumbar epidural anaesthesia, big toe skin temperature increases and is associated with a compensatory decrease of thumb temperature. The purpose of the present study was to examine whether thumb-big toe temperature differences were affected by age. Following the attachment of temperature probes at the digital pad of the right big toe and the right thumb, lumbar epidural anaesthesia at L2/3...

Aspergillus nidulans early endosomes display characteristic long-distance bidirectional motility. Simultaneous dual-channel acquisition showed that the two Rab5 paralogues RabB and RabA colocalize in these early endosomes and also in larger, immotile mature endosomes. However, RabB-GTP is the sole recruiter to endosomes of Vps34 PI3K (phosphatidylinositol-3-kinase) and the phosphatidylinositol-...

OBJECTIVE To evaluate melatonin secretion in adult hypopituitary patients with Growth Hormone deficiency (AGHD) on and off replacement therapy. SUBJECTS AND METHODS We studied 48 subjects: 12 (6 males) untreated AGHD (AGHDnt), 20 (10 males) treated AGHD (AGHDt) and 16 healthy subjects (8 males) as control group (CG). We measured urinary 6-sulfatoxymelatonin (6-SM) in total (24 h samples), noc...

The Borodin–Kostochka Conjecture states that for a graph G $G$ , if Δ ( ) ≥ 9 ${\rm{\Delta }}(G)\ge 9$ and ω ≤ − 1 $\omega (G)\le {\rm{\Delta }}(G)-1$ then χ $\chi . We prove the P 5 gem $({P}_{5},\text{gem})$ -free graphs, is, graphs with no induced ${P}_{5}$ K ∨ 4 ${K}_{1}\vee {P}_{4}$

The interrelationships between serum levels of amiodarone, desethylamiodarone, and reverse T3, and changes in the corrected QT interval (delta QTc) were examined in 22 patients during long-term treatment with amiodarone. At 1, 3, and 6 months of follow-up, the correlation coefficient between serum levels of amiodarone or desethylamiodarone and reverse T3 ranged from 0.01 to -0.2 (p greater than...

let $mathfrak{a}$ be an algebra. a linear mapping $delta:mathfrak{a}tomathfrak{a}$ is called a textit{derivation} if $delta(ab)=delta(a)b+adelta(b)$ for each $a,binmathfrak{a}$. given two derivations $delta$ and $delta'$ on a $c^*$-algebra $mathfrak a$, we prove that there exists a derivation $delta$ on $mathfrak a$ such that $deltadelta'=delta^2$ if and only if either $delta'=0$...