A new, simple, and sensitive spectrophotometric method for the determination of certain tricyclic antidepressants, belonging to the dibenzazepine class of drugs, has been developed. The proposed method is based on the reaction of imipramine hydrochloride (IPH), desipramine hydrochloride (DPH), clomipramine hydrochloride (CPH), trimipramine maleate (TPM) or opipramol (OPP) with iron(III), and su...

Pulmonary hemosiderosis in infants (< 1 year of age) is a syndrome characterized by pulmonary hemorrhage and hemosiderin-laden macrophages. As there are multiple incompletely understood etiologies regarding this syndrome, this paper discusses the etiologic and pathophysiologic mechanisms, -with particular attention to Heiner’s syndrome, Wegener’s granulomatosis, and the toxigenic mold Stachybot...

Abstract Background Inadvertent perioperative hypothermia (IPH) defined as core temperature below 36.0 °C is a common complication of general anesthesia with prevalence up to 70%. Warming peripheral tissues prior induction reduces the central gradient, thereby minimizing heat loss due redistribution, after anesthesia. This study aimed evaluate effect prewarming on post-induction and incidence i...

INTRODUCTION The possibility of developing idiopathic portal hypertension has been described with thiopurine treatment despite compromises the prognosis of these patients, the fact its true prevalence is unknown. MATERIAL AND METHODS A cross-sectional study was conducted in a cohort of inflammatory bowel disease (IBD) patients followed at our unit, to determine the prevalence of diagnosis of ...

The present study was designed to evaluate the effect of Polyherbal formulation (250 mg/kg and 500 mg/kg body weight) on Isoprenaline hydrochloride induced myocardial necrosis in experimental rats. The herbal formulation that was prepared has synergistic effect and will reduce the toxicity of individual herbs. Isoprenaline hydrochloride (IPH) induced myocardial infarction was confirmed by distu...

AbstractBackground and aims Lipoprotein(a) is an independent risk factor for cardiovascular disease recurrent ischemic stroke. levels are known to be associated with carotid artery stenosis, but the relation of lipoprotein(a) atherosclerotic plaque composition morphology less known. We hypothesize that higher lipoprotein(a)-related SNPs a more vulnerable this effect sex-specif...

Schwarz methods are attractive parallel solvers for large-scale linear systems obtained when partial differential equations are discretized. For hybridizable discontinuous Galerkin (HDG) methods, this is a relatively new field of research, because HDG methods impose continuity across elements using a Robin condition, while classical Schwarz solvers use Dirichlet transmission conditions. Robin c...

RATIONALE Intraplaque hemorrhage (IPH) drives atherosclerosis through the dual metabolic stresses of cholesterol-enriched erythrocyte membranes and pro-oxidant heme/iron. When clearing tissue hemorrhage, macrophages are typically seen storing either iron or lipid. We have recently defined hemorrhage-associated macrophages (HA-mac) as a plaque macrophage population that responds adaptively to IP...