Background—Anal fissure is perpetuated by high sphincter pressures and secondary local ischaemia. Pharmacological approaches include topical nitrates and botulinum toxin (BT) which act to reduce anal pressure. BT lowers anal pressure by preventing acetylcholine release from nerve terminals while topical nitrates act by donating nitric oxide (NO). The aims of the present study were to compare th...

one of the major obstacles of bt production as a biopesticide is its expensive bioprocess and fermentation. therefore, the objective of the present study was to optimize growth condition and develop a low-cost bioprocess for mass production of a native coleopteran-effective bacillus thuringiensis (bt) strain (kh4) based on agricultural wastes, at incubator and batch fermenter level. preliminary...

Field trials were conducted from 2007 to 2010 to compare grain fumonisin levels among non-Bt maize hybrids and Bt hybrids with transgenic protection against manual infestations of European corn borer (ECB) and Western bean cutworm (WBC). HPLC and ELISA were used to measure fumonisin levels. Results of the methods were highly correlated, but ELISA estimates were higher. Bt hybrids experienced le...

RATIONALE Bronchial thermoplasty (BT) is a bronchoscopic procedure in which controlled thermal energy is applied to the airway wall to decrease smooth muscle. OBJECTIVES To evaluate the effectiveness and safety of BT versus a sham procedure in subjects with severe asthma who remain symptomatic despite treatment with high-dose inhaled corticosteroids and long-acting beta(2)-agonists. METHODS...

PURPOSE There are limited data at a population level on adjuvant brachytherapy (BT) practice for uterine corpus malignancies. The aims of the current study were to describe BT practice for this disease in New South Wales (NSW), to assess quality of BT, and to determine if a caseload effect on quality exists. MATERIAL AND METHODS Patient, tumour, and treatment related data were collected from ...

Accessible online at: www.karger.com/journals/ene Therapeutic use of botulinum toxin type A (BT-A) has dramatically increased after its introduction by Scott [1] in 1980. It now provides help for patients suffering from muscle hyperactivity disorders in neurology, rehabilitation medicine, pediatrics, otorhinolaryngology, ophthalmology, urology and many other areas. Recently, it has been recogni...

This meta-analysis assessed the efficacy and safety of a novel intervention for asthma, bronchial thermoplasty (BT), in patients with moderate-to-severe persistent asthma. An electronic literature search identified three randomized controlled trials (RCT) of BT that recruited 421 patients in total. Outcomes of interest were the Asthma Quality of Life Questionnaire (AQLQ) score, morning peak exp...

Exposure to Bacillus thuringiensis (Bt) toxins in low- and moderate-dose transgenic crops may induce sublethal effects and increase the rate of Bt resistance evolution, potentially compromising control efficacy against target pests. We tested this hypothesis using the fall armyworm Spodoptera frugiperda, a major polyphagous lepidopteran pest relatively tolerant to Bt notorious for evolving fiel...

In 1995, ears of a experimental inbred (CG59-2) containing a synthetic Bacillus thuringiensis Cry IA (b) gene driven by PEPC, pith and pollen promoters and artificially infested with Ostrinia nubilalis (Hübner) larvae in small plot studies were free from insect damage, whereas 40-50% of the corresponding non-Bt inbred ears were damaged. Bt inbred ears that were inoculated with Aspergillus flavu...