In this paper we investigate the use of compactly supported RBF kernels for nonlinear function estimation with LS-SVMs. The choice of compact kernels recently proposed by Genton may lead to computational improvements and memory reduction. Examples however illustrate that compactly supported RBF kernels may lead to severe loss in generalization performance for some applications, e.g. in chaotic ...

Nitric oxide (NO) is a vasodilator substance controlling renal papillary blood flow (PBF) in the rat. In this study we have evaluated the role of AT1 angiotensin II receptors as modulators of the whole kidney and papillary vasoconstrictor effects induced by the acute or chronic inhibition of NO synthesis. Experiments have been performed in anesthetized, euvolemic Munich-Wistar rats prepared for...

This paper presents a new sequential multi-category classifier using radial basis function (SMC-RBF) network for real-world classification problems. The classification algorithm processes the training data one by one and builds the RBF network starting with zero hidden neuron. The growth criterion uses the misclassification error, the approximation error to the true decision boundary and a dist...

Pressure-dependent urine production is considered to be a major factor in long-term blood pressure control. The phenomenon has been well characterized for fixed levels of renal perfusion pressure (RPP), but the influence of physiological fluctuations in RPP and spontaneous variations in renal blood flow (RBF) on short-term urine flow (UV) remain unclear. To clarify this issue, we studied the in...

PURPOSE To investigate the effect of intravitreal bevacizumab (IVB) injections for macular edema secondary to acute branch retinal vein occlusion on the retinal microcirculation. METHODS The study was a prospective, interventional case series. Central macular thickness using spectral-domain optical coherence tomography and retinal blood flow (RBF) in untreated eyes with macular edema secondar...

In a radial basis function (RBF) network, the RBF centers and widths can be evolved by a cooperative-competitive genetic algorithm. The set of genetic strings in one generation of the algorithm represents one REP network, not a population of competing networks. This leads to moderate computation times for the algorithm as a whole. Selection operates on individual RBFs rather than on whole netwo...

The response surface methodology (RSM), which typically uses quadratic polynomials, is predominantly used for metamodeling in crashworthiness optimization because of the high computational cost of vehicle crash simulations. Research shows, however, that RSM may not be suitable for modeling highly nonlinear responses that can often be found in impact related problems, especially when using limit...

Sensor systems are not always equipped with the ability to track targets. Sudden maneuvers of a target can have a great impact on the sensor system, which will increase the miss rate and rate of false target detection. The use of the generic particle filter (PF) algorithm is well known for target tracking, but it can not overcome the degeneracy of particles and cumulation of estimation errors. ...

PURPOSE To investigate whether nitric oxide (NO) contributes to the regulation of retinal circulation during hypercapnia in cats. METHODS NG-nitro-L-arginine-methylester (L-NAME; n=8), a NOS inhibitor; NG-nitro-D-arginine-methylester (D-NAME; n=6), the inactive isomer; or phosphate-buffered saline (PBS; n=8) was injected intravitreously into the cat's eye. A selective neuronal nitric oxide sy...

BACKGROUND The increase of intraabdominal pressure to 10 mmHg provokes a decrease of renal blood flow (RBF). Pneumoperitoneum during laparoscopic techniques with intra-abdominal pressure (IAP) to 15 mmHg, results in a decrease in RBF, urine output and glomerular filtration rate (GFR). PURPOSE Analyze the changes in RBF, urine output an GFR in a porcine experimental model during open vs laparo...