IA-1 is a novel cDNA originally isolated from a human insulinoma subtraction library (ISL-153). It encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. IA-1 transcripts have been found thus far only in tumors of neuroendocrine origin. Clinical studies have shown that IA-1 is a sensitive marker for neuroendocrine differentiation of human lung tumor...

OBJECTIVE This study was designed to assess the usefulness of transperineal ultrasonography (US) for the determination of imperforate anus (IA) type. MATERIALS AND METHODS From January 2000 to December 2004, 46 of 193 patients with an IA underwent transperineal US prior to corrective surgery. Sonographic findings were reviewed to identify the presence of internal fistulas and to determine "di...

The initiation of many antigen-specific, T-dependent immune responses requires the participation of accessory cells that express Ia antigens (1, 2). Recent evidence indicates that the Ia antigen expression of macrophages, a principle class of accessory cells, is regulated by lymphokines: Ste inman et al. (3) have reported that culture supernatants of Trypanosoma cruzi-activated spleen cells enh...

The midgut proteinases from a Bacillus thuringiensis-susceptible (IA-S) and four laboratory-selected resistant strains (KS-SC, KS-NE, IA-1, and IA-3) of European corn borer (Ostrinia nubilalis) were characterized using three synthetic substrates, Na-benzoyl-L-arginine p-nitroanilide (BApNA) for trypsin-like, Nsuccinyl-ala-ala-pro-phe p-nitroanilide (SAAPFpNA) for chymotrypsin-like, and N-succin...

OBJECTIVE To study the extent of Internet addiction (IA) and its association with depression in Thai medical students. METHODS A cross-sectional study was conducted at Faculty of Medicine, Ramathibodi Hospital. Participants were first- to fifth-year medical students who agreed to participate in this study. Demographic characteristics and stress-related factors were derived from self-rated que...

The initiation of many antigen-specific, T-dependent immune responses requires the participation of accessory cells that express Ia antigens (1, 2). Recent evidence indicates that the Ia antigen expression of macrophages, a principle class of accessory cells, is regulated by lymphokines: Ste inman et al. (3) have reported that culture supernatants of Trypanosoma cruzi-activated spleen cells enh...

BACKGROUND Type 1 diabetes (TID) is characterized by a loss of pancreatic islet beta cell function resulting in loss of insulin production. Genetic and environmental factors may trigger immune responses targeting beta cells thus generating islet antibodies (IA). Immune response pathways involve a cascade of events, initiated by cytokines and chemokines, producing inflammation which can result i...

The IA-64 architecture provides new opportunities and challenges for implementing an improved set of transcendental functions. Using several novel polynomial-based table-driven techniques, we are able to provide new algorithms for the transcendental functions. Major improvements include an accuracy level of about 0.6 ulps (units in the last place) and forward trigonometric functions that have a...

The IA-64 architecture, co-developed by HP and Intel, is going to reach market mid-2000 with Merced as its first implementation. Major industry players have endorsed this new architecture and technical details are gradually becoming publicly available. However, the complete architecture will not be fully disclosed until machines become available. To provide for early availability of Linux on IA...