نتایج جستجو برای: γ aminobutyric acid
تعداد نتایج: 814207 فیلتر نتایج به سال:
Cerebral ischemia not only causes pathological changes in the ischemic areas but also induces a series of secondary changes in more distal brain regions (such as the contralateral cerebral hemisphere). The impact of supratentorial lesions, which are the most common type of lesion, on the contralateral cerebellum has been studied in patients by positron emission tomography, single photon emissio...
The title compound, C(12)H(21)NO(4), a γ-aminobutyric acid derivative, crystallizes with two mol-ecules in the asymmetric unit. The crystal structure is stabilized by inter-molecular N-H⋯O and O-H⋯O hydrogen bonds, forming a strand. An intramolecular N-H⋯O hydrogen bond is also observed.
CONTEXT Disturbances in markers of cortical γ-aminobutyric acid neurotransmission are a common finding in schizophrenia. The nature of γ-aminobutyric acid neurotransmission (hyperpolarizing or depolarizing) depends on the local intracellular chloride concentration. In the central nervous system, the intracellular chloride level is determined by the activity of 2 cation-chloride transporters, NK...
Malus baccata (L.) Borkh. is one of the most widely used rootstocks in apple-producing region Northern China. However, early growing season, apple roots are often subjected to suboptimal low root-zone temperatures. The regulatory effects exogenous γ-aminobutyric acid (GABA) on both shunt (GABA shunt) and respiratory activity under temperatures remain unknown. To explore physiological basis for ...
BACKGROUND Ghrelin and obestatin are two gut-derived peptides originating from the same ghrelin/obestatin prepropeptide gene (GHRL). While ghrelin stimulates growth hormone (GH) secretion and food intake and inhibits γ-aminobutyric-acid synaptic transmission onto GHRH (Growth Hormone Releasing Hormone) neurons, obestatin blocks these effects. In Humans, GHRL gene polymorphisms have been associa...
BACKGROUND Evoking spinal release of acetylcholine (ACh) produces antinociception in normal animals and reduces hypersensitivity after nerve injury, and some studies suggest that ACh-mediated analgesia relies on γ-aminobutyric acid (GABA)-ergic signaling in the spinal cord. In this study, the authors tested the spinal mechanisms underlying the antihypersensitivity effects of donepezil, a centra...
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