نتایج جستجو برای: β blockers
تعداد نتایج: 196219 فیلتر نتایج به سال:
BACKGROUND Various guidelines are available outlining optimal therapy for patients with acute myocardial infarction. Canadian institutions providing care for such patients have been encouraged to evaluate their care processes using specific indicators. OBJECTIVE To determine the proportion of patients with acute myocardial infarction discharged from a single health authority for whom acetylsa...
BACKGROUND The authors evaluated the effect of preoperative β-blocker use on early outcomes in patients undergoing coronary artery bypass grafting (CABG) in Japan. METHODS The authors analyzed 34,980 cases of isolated CABGs, performed between 2008 and 2011, at the 333 sites recorded in the Japanese Cardiovascular Surgical Database. In addition to the use of multivariate models, a one-to-one m...
BACKGROUND Despite limited evidence of effect, β-blocker continuation has become a national quality improvement metric. OBJECTIVE To determine the effect of β-blocker continuation on outcomes in patients undergoing elective noncardiac surgery. DESIGN, SETTING, AND PATIENTS The Surgical Care and Outcomes Assessment Program is a Washington quality improvement benchmarking initiative based on ...
BACKGROUND The evidence supporting the use of β-blockers in patients with acute coronary syndrome after successful percutaneous coronary intervention has been inconsistent and scarce. METHODS AND RESULTS Between March 1, 2009, and December 30, 2014, a total of 3180 eligible patients with acute coronary syndrome undergoing percutaneous coronary intervention were consecutively enrolled. The pri...
BACKGROUND Perioperative metoprolol increases postoperative stroke. Animal studies indicate that the mechanism may be related to attenuated β(2)-adrenoreceptor-mediated cerebral vasodilatation. The authors therefore conducted a cohort to study whether the highly β(1)-specific β-blocker (bisoprolol) was associated with a reduced risk of postoperative stroke compared with less selective β-blocker...
Cancer is the leading cause of death in the USA, and the incidence of cancer increases dramatically with age. Beta-adrenergic blockers appear to have a beneficial clinical effect in cancer patients. In this paper, we review the evidence of an association between β-adrenergic blockade and cancer. Genetic studies have provided the opportunity to determine which proteins link β-adrenergic blockade...
IMPORTANCE The effectiveness of perioperative β-blockade in patients undergoing noncardiac surgery remains controversial. OBJECTIVE To determine the associations of early perioperative exposure to β-blockers with 30-day postoperative outcome in patients undergoing noncardiac surgery. DESIGN, SETTING, AND PATIENTS A retrospective cohort analysis evaluating exposure to β-blockers on the day o...
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