Context: In case of diabetes, persistent and chronic hyperglycaemia may generate free radicals and reactive oxygen species (ROS), which trigger an oxidative stress. Garlic (Allium sativum) is a rich source of bioactive compounds and is used in folk medicine for the treatment of various diseases, including diabetes. Besides, α-tocopherol and magnesium have been shown to possess antioxidative pro...

The glycosylation of αand δ-tocopherols using Klebsiella pneumoniae and cyclodextrin glucanotransferase (CGTase) was investigated. K. pneumoniae converted αand δ-tocopherols into the corresponding β-glucosides in 10 and 8% yield, respectively. CGTase glycosylated α-tocopheryl β-glucoside to α-tocopheryl β-maltoside (51%) and αtocopheryl β-maltotrioside (35%). On the other hand, δ-tocopheryl β-g...

Objective. To investigate vascular endothelial function (VEF) responses to a single low-density lipoprotein (LDL) apheresis session in hypercholesterolemic patients undergoing chronic treatment. Methods. We measured brachial artery flow-mediated dilation (FMD), plasma lipids, vitamin E (α- and γ-tocopherol), markers of oxidative/nitrative stress (malondialdehyde (MDA) and nitro-γ-tocopherol (NG...

Vitrification of preantral follicles is a promising technique to preserve female fertility. The aim the present study was evaluate effect supplementation α-tocopherol in vitrification solution on viability, lipid peroxidation and mRNA expression superoxide dismutases (SOD1 SOD2) vitrified cultured ovine at day-6 day-12. Preantral (200-300 µm) were isolated from ovaries by mechanical method dist...

This study represents the first report on the chemical composition and biological activity of Trifolium angustifolium var. angustifolium. The major components of the essential oil were identified as hexatriacontene (23.0%), arachidic acid (15.5%) and α-selinene (10.0%). The main constituents of the fatty acid obtained from the petroleum ether extract were identified as palmitic acid (29.8%), li...

The objective of the present study was to determine if treatment of diabetic rats with D-α-tocopherol could prevent the changes in glomerular and tubular function commonly observed in this disease. Sixty male Wistar rats divided into four groups were studied: control (C), control treated with D-α-tocopherol (C + T), diabetic (D), and diabetic treated with D-α-tocopherol (D + T). Treatment with ...

An experiment was conducted using 42 IVRI 2CQ rats to evaluate the effects of three antioxidants, ascorbic acid, l methionine or α tocopherol alone, or chelator CaNa2EDTA alone or along with antioxidant α tocopherol, on lead accumulation, status of lipid peroxidation, and of copper and zinc concentration in cardiac tissue of lead-treated rats. Lead was given intraperitoneally as 1% lead acetate...

this study represents the first report on the chemical composition and biological activity of trifolium angustifolium var. angustifolium. the major components of the essential oil were identified as hexatriacontene (23.0%), arachidic acid (15.5%) and α-selinene (10.0%). the main constituents of the fatty acid obtained from the petroleum ether extract were identified as palmitic acid (29.8%), li...

BACKGROUND Angiotensin II (Ang II) and high-fat diet are implicated in causing pathological changes in the vascular endothelium, brain, kidney and liver. The association of aneurysm leading to histopathological changes in the splenic compartment remains elusive. Further, the salubrious credentials of antioxidants, especially α-tocopherol and β-carotene in the resolution of splenic pathology hav...