Since 2007, Zika virus has spread through the Pacific Islands and the Americas. Beginning in 2016, women in Brownsville, Texas, USA, were identified as possibly being exposed to Zika virus during pregnancy. We identified 18 pregnant women during 2016-2017 who had supportive serologic or molecular test results indicating Zika virus or flavivirus infection. Two infants were evaluated for congenit...

Zika virus is an emerging mosquito-borne pathogen that is associated with Guillain-Barré syndrome in adults and microcephaly and other neurological defects in newborns. Despite being declared an international emergency by the World Health Organization, comparatively little is known about its biology. Here, we investigate the strategies employed by the virus to suppress the host antiviral respon...

OBJECTIVE The recent spreading of Zika virus represents an emerging global health threat. As such, it is attracting public interest worldwide, generating a great amount of related Internet searches and social media interactions. The aim of this research was to understand Zika-related digital behavior throughout the epidemic spreading and to assess its consistence with real-world epidemiological...

Zika virus transmission is primarily vector-borne, mainly via Aedes mosquitoes. The virus can also be found in various body fluids and transmission by sexual contact has also been reported. Aedes aegypti, the principal vector, is found in tropical and subtropical climates and adapts well to urban areas, living in and around human habitations. The areas affected by Zika virus lie within areas af...

BACKGROUND The World Health Organization's and Centers for Disease Control and Prevention's definition of Zika infection are symptoms of fever, rash, joint pain, myalgia, headache and conjunctivitis. The diagnosis of Zika infection is based on the clinical history, physical examination and laboratory investigations which includes blood and urine Zika virus Polymerase Chain Reaction. CASE PRES...

OBJECTIVE To review the state of knowledge about diagnostic testing for Zika virus infection and identify areas of research needed to address the current gaps in knowledge. METHODS We made a non-systematic review of the published literature about Zika virus and supplemented this with information from commercial diagnostic test kits and personal communications with researchers in European prep...

Dear Editor: The epidemic of Zika virus infection in Brazil has lead to the description of new complications and manifestations such as Guillain-Barré syndrome in adults and microcephaly in newborns. Zika virus is a flavivirus transmitted to humans primarily through the bite of an infected Aedes species mosquito. It was first isolated and described in Africa, later spreading to Asia, Micronesia...

Zika virus transmission is primarily vector-borne, mainly via Aedes mosquitoes. The virus can also be found in various body fluids and transmission by sexual contact has also been reported. Aedes aegypti, the principal vector, is found in tropical and subtropical climates and adapts well to urban areas, living in and around human habitations. The areas affected by Zika virus lie within areas af...

Editorials 711 The Spondweni serogroup includes Zika and Spondweni viruses. Both viruses have been historically misidentified and their diseases have been misdiagnosed due to their serological cross-reactivity and similar clinical presentations. Early case reports indicate a subset of patients present with clinical manifestations suggestive of serious illness. Flaviviruses have a high serologi-...

Thus, virus-contaminated materials such as surgical instruments can be decontaminated by heat. We also found that Zika virus infectivity was highest after adjusting the stock to a pH of ≈9 (Figure, panel F). In contrast, adjusting Zika virus to pH 12 or to <pH 4 abrogated infectivity (Figure, panel F). Finally, we analyzed whether gloves routinely used in BSL-2 laboratories protect against Zika...