The 2002 Keystone symposia held in Taos, New Mexico (21-26 February) saw the convergence of two related fields; Epigenetics in Development and Disease, and RNA Interference, Cosuppression and Related Phenomena. The meeting highlights presented here concentrate upon the sessions within the Epigenetics in Development and Disease meeting, although there were joint sessions which will also be discu...

After our work [1] was published, Frink and Meißner [2] pointed out that the O(q3) three-flavour meson-baryon chiral Lagrangian presented there was not minimal. Here, we discuss their findings and revise ours accordingly. We find out eight monomials in the Lagrangian presented in [1] are not independent, but in addition, two monomials were wrongly discarded there which, as a result, makes the a...

November 2005, Vol. 95, No. 11 SAMJ Uncertainty as to the cause or causes of sudden and unexpected infant death and difficulty in excluding the possibility of infanticide, even after the performance of a ‘complete’ autopsy, was graphically illustrated in the London courts recently. A mother wrongly convicted of killing her two sons had her conviction quashed, and the eminent paediatrician who h...

Acute alcoholic pancreatitis was undiagnosed in a patient with anorexia nervosa who subsequently developed pancreatic ascites and oedema, wrongly attributed to protein malnutrition alone. She became hyperphagic in an attempt to reverse the malnutrition and hence the abdominal swelling, indicating that the goal of attaining a thin shape was the major determinant of the eating disorder in this pa...

A misclassified size-biased Borel Distribution (MSBBD), where some of the observations corresponding to x = c + 1 are wrongly reported as x = c with probability α, is defined. Various estimation methods like the method of maximum likelihood (ML), method of moments, and the Bayes estimation for the parameters of the MSBB distribution are used. The performance of the estimators are studied using ...

A firewall administrator often needs to update a given firewall, to take account of evolving security requirements or to correct a wrongly classified packet. We look at the problem of firewall update, mainly from an axiomatic viewpoint. An axiom for firewall update is a property which any reasonable method of updating should fulfill. We propose a number of such axioms. We also give some simple ...

The correct diagnosis was initially suspected in 32 (53%) of 60 patients with ectopic pregnancy who attended an accident and emergency department. Incorrect diagnoses were made because ectopic pregnancy was not considered or because relevant symptoms and signs were missed or misinterpreted. Three patients had been 'sterilized'. Twenty-four patients (40%) had abdominal pain or vaginal bleeding f...

BACKGROUND Using hybrid approach for gene selection and classification is common as results obtained are generally better than performing the two tasks independently. Yet, for some microarray datasets, both classification accuracy and stability of gene sets obtained still have rooms for improvement. This may be due to the presence of samples with wrong class labels (i.e. outliers). Outlier dete...

Lung infections infrequently simulate cancer, and their differentiation, based on imaging findings, can sometimes be difficult. The infections may be fungal, mycobacterial, parasitic or, rarely, viral. A biopsy is required to prove the infectious nature of the lesions. A specific diagnosis is necessary for initiation of appropriate therapy. We report four cases of chronic pulmonary infections, ...

The target article diagnoses a dominance of liberal viewpoints with little evidence, promotes a conservative viewpoint without defining it, and wrongly projects the U.S. liberal-conservative spectrum to the whole field of social psychology. Instead, we propose to anticipate and reduce mixing of theorizing and ideology by using definitions that acknowledge divergence in perspective, and promote ...