D-002, a mixture of six higher aliphatic alcohols purified from beeswax, has been shown to produce anti-inflammatory effects in experimental models, devoid of gastrotoxic or hepatotoxic effects. Some studies have demonstrated that D-002 exerts analgesic effects, but just related to its anti-inflammatory action. The objective of this study was to compare the effects of D-002, naproxen, aspirin a...

Calendula Of.cinalis (Asteraceae) is widely used in traditional medicine as an anti-in.ammatory agent and has also been reported to have anti-bacterial, anti-fungal and anti-viral activities.  Sesquiterpene glycosides, saponins, triol, triterpenes and .avonoids are observed in its composition. The present study was designed to evaluate the antinociceptive effect of hydro-alcoholic extract of Ca...

Background: Herbal medical compounds and their major constituent have been used in the management and treatment of opioid withdrawal syndrome and pain. This study was carried out to clarify the effect of curcumin, the major compound of turmeric, on morphine withdrawal syndrome in mouse model and its possible mechanisms of pain relieving activity by assessing in writhing test as a model of visce...

Abstract Background Macropanax dispermus is traditionally used to treat various diseases by ethnic people. The present research reports the pharmacological properties with phytochemical profiling of crude extracts M. leaves (MDML), its n-hexane (MDHL), carbon tetrachloride (MDTL), chloroform (MDCL), ethyl acetate (MDEL), and aqueous (MDAL) fractions, methanol stem barks (MDMS). in vitro thrombo...

extracts obtained from the petals of rosa damascena (rosaceae) are used in iranian folk medicine as remedies for the treatment of some inflammatory diseases. in this study the hydroalcoholic extract and essential oil of the plant were investigated for its possible anti-inflammatory and analgesic activities. the extract was administered at the doses (p.o.) of 250, 500 and 1000?mg/kg and the dose...

ziziphora tenuior has been used in iranian folk medicine as an analgesic and for treament of digestive diseases.this study was designed to investigate the antinociceptive effects of hydroalcoholic extract of z. tenuior on visceral pain and its possible involvement in opioidergic and serotoninergic systems in male albino n-mri mice. antinociceptive effect of was determined by writhing test as a ...