Objective: to study the effects of GHK peptide and its structure analogues on mechanisms innate immunity lipid peroxidation in wound. Materials methods. The experiments were performed 70 male Wistar rats. skin wound was modeled by applying a full-layer with an area 250 mm2 animal's back. peptides Gly-His-Lys (GHK), D-Ala-Gly-His-Lys (D-Ala-GHK), Gly-His-Lys-D-Ala (GHK-D-Ala) used doses 0.5 μg/k...

BACKGROUND For the majority of patients with osteoarthritis (OA), joint replacement is a successful intervention for relieving chronic joint pain. However, between 10-30% of patients continue to experience chronic pain after joint replacement. Evidence suggests that a risk factor for chronic pain after joint replacement is the severity of acute post-operative pain. The aim of this randomised co...

OBJECTIVE Several well-accepted classification systems are available for diabetic foot ulcers. However, there are only a few and scientifically not validated severity scores. The aim of this study was to establish a new wound-based clinical scoring system for diabetic foot ulcers suitable for daily clinical practice anticipating chances for healing and risk of amputation. RESEARCH DESIGN AND ...

background: plants and their phytochemicals have immense potential for the management of different types of wound. salvia multicaulis vahl. is an evergreen shrub species, which traditionally used as a wound healing agent. objective: the aim of the present study is to evaluate phytochemicals and wound healing activity of s. multicaulis in an excision wound model. methods: preliminary phytochemic...

introduction: impaired wound healing in diabetic patients is a major clinical problem, which is associated with significant morbidity and mortality. estrogen has positive effects on neoangiogenesis, reepithelialization and cell proliferation. in this research, effect of estrogen on wound healing in diabetic male rats was investigated. methods: this study was performed on male wistar rats (body ...

Chronic wounds that stall at the inflammatory phase of healing may create several life-threatening complications such as tissue damage, septicemia, and organ failures. In order to prevent these adverse clinical outcomes accelerate wound process, it is crucial monitor status in real-time so immediate therapeutic interventions can be implemented. addition, continuous monitoring drug overdose site...

Introduction: A periodontal treatment includes surgical and nonsurgical therapy which the successful wound healing after is influenced by many local systemic factors. One factor that influences stress. Recent studies have shown stress plays a role in predicting severity of pain, disease, can even inhibit healing. This article aims to review how inhibits Review: Stress occur as result stressors ...

objective: martynia annua l. (m. annua), (martyniaccae) has been traditionally used in the treatment of epilepsy, sore throat and inflammatory disorders. the leaf paste is used topically on tuberculosis of the lymphatic glands and wounds of domestic animals. tephrosia purpurea (t. purpurea), (fabaceae) has been used traditionally as a remedy for asthma, gonorrhea, rheumatism and ulcers. this st...

In the present investigation, methanolic extract of Mimusops elengi  leaves were evaluated for wound healing activity. Entire wound healing process is complex series of events that begins at the moment of injury and can continue for months to years. Methanolic extract of Mimusops elengi leaves were examined for wound healing activity in the form of ointment by the excision, the incision and ...